ArticleScientific reports2017
A method for estimating intracellular ion concentration using optical nanosensors and ratiometric imaging.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Review
- Perspective on fluorescence cell imaging with ionophore-based ion-selective nano-optodes.Biomicrofluidics · 2022Article
- Neuron devices: emerging prospects in neural interfaces and recognition.Microsystems & nanoengineering · 2022Review
- Optimizing Calcium Detection Methods in Animal Systems: A Sandbox for Synthetic Biology.Biomolecules · 2021Review
- LipiSensors: Exploiting Lipid Nanoemulsions to Fabricate Ionophore-Based Nanosensors.Biosensors · 2020Article
- Upconversion nanoparticles as intracellular pH messengers.Analytical and bioanalytical chemistry · 2020Article
- Extended dynamic range imaging for noise mitigation in fluorescence anisotropy imaging.Journal of biomedical optics · 2020Article
- A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(ii) ion determination in living cells.Chemical communications (Cambridge, England) · 2020Article
- Real-time particle-by-particle detection of erythrocyte-camouflaged microsensor with extended circulation time in the bloodstream.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Recent Developments in Nanosensors for Imaging Applications in Biological Systems.Annual review of analytical chemistry (Palo Alto, Calif.) · 2019Review
- Imaging Sodium Flux during Action Potentials in Neurons with Fluorescent Nanosensors and Transparent Microelectrodes.ACS sensors · 2018Article
- Optical Probes for Neurobiological Sensing and Imaging.Accounts of chemical research · 2018Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Optical nanoparticle (NP)-based sensors have been widely implemented as tools for detection of targeted ions and biomolecules. The NP sensing platform offer a modular design that can incorporate different sensing components for greater target specificity and the ability to tune the dynamic range, as well as encapsulation of multiple dyes to generate a ratiometric signal with varying spectra. Despite these advantages, demonstrating quantitative ion imaging for intracellular measurement still possess a major challenge. Here, we describe fundamentals that enable intracellular validation of this approach using ion-selective nanosensors for investigating calcium (Ca
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Registered trials
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