ReviewMaterials (Basel, Switzerland)2010
Toxicity of Transition Metal Oxide Nanoparticles: Recent Insights from in vitro Studies.
Review in Materials (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
45 citing papers in PubMed.
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- Antibacterial impact of biosynthesized zinc oxide nanoparticles on uropathogenic Escherichia coli and in vivo assessment of physiological and histological alterations.Scientific reports · 2025Article
- Characterization and Cellular Toxicity Studies of Commercial Manganese Oxide Nanoparticles.Nanomaterials (Basel, Switzerland) · 2024Article
- Understanding the role of solvents in bottom-up synthesis of multi-element hydroxides.RSC advances · 2024Article
- Visualizing the 4D Impact of Gold Nanoparticles on DNA.International journal of molecular sciences · 2023Article
- MgO Nanoparticles Obtained from an Innovative and Sustainable Route and Their Applications in Cancer Therapy.Nanomaterials (Basel, Switzerland) · 2023Article
- Article
- Transition Metal Sensing with Nitrogenated Holey Graphene: A First-Principles Investigation.Molecules (Basel, Switzerland) · 2023Article
- Ultrasmall, elementary and highly translational nanoparticle X-ray contrast media from amphiphilic iodinated statistical copolymers.Acta pharmaceutica Sinica. B · 2023Article
- Nanoparticles Induced Oxidative Damage in Reproductive System and Role of Antioxidants on the Induced Toxicity.Life (Basel, Switzerland) · 2023Review
- Retinal cytotoxicity of silica and titanium dioxide nanoparticles.Toxicology research · 2022Article
- Metal/Metalloid-Based Nanomaterials for Plant Abiotic Stress Tolerance: An Overview of the Mechanisms.Plants (Basel, Switzerland) · 2022Review
- Toxicity of metal-based nanoparticles: Challenges in the nano era.Frontiers in bioengineering and biotechnology · 2022Review
- Antimicrobial Coating: Tracheal Tube Application.International journal of nanomedicine · 2022Review
- Complexity of the Nano-Bio Interface and the Tortuous Path of Metal Oxides in Biological Systems.Antioxidants (Basel, Switzerland) · 2021Review
- Protective Effect ofNanomaterials (Basel, Switzerland) · 2021Article
- Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology.Journal of toxicology · 2021Review
- Toxicity of TiOInternational journal of molecular sciences · 2020Article
- Novel Polymeric Micelles-Coated Magnetic Nanoparticles for In Vivo Bioimaging of Liver: Toxicological Profile and Contrast Enhancement.Materials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanotechnology has evolved to play a prominent role in our economy. Increased use of nanomaterials poses potential human health risk. It is therefore critical to understand the nature and origin of the toxicity imposed by nanomaterials (nanotoxicity). In this article we review the toxicity of the transition metal oxides in the 4th period that are widely used in industry and biotechnology. Nanoparticle toxicity is compellingly related to oxidative stress and alteration of calcium homeostasis, gene expression, pro-inflammatory responses, and cellular signaling events. The precise physicochemical properties that dictate the toxicity of nanoparticles have yet to be defined, but may include element-specific surface catalytic activity (e.g., metallic, semiconducting properties), nanoparticle uptake, or nanoparticle dissolution. These in vitro studies substantially advance our understanding in mechanisms of toxicity, which may lead to safer design of nanomaterials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.