Evidence map›Paper›PMID 28883097›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2018

Survival of very preterm infants admitted to neonatal care in England 2008-2014: time trends and regional variation.

Shalini Santhakumaran, Yevgeniy Statnikov, Daniel Gray, Cheryl Battersby, Deborah Ashby, Neena Modi, Medicines for Neonates Investigator Group

Abstract read
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. The role of prophylactic arginine supplementation for prevention of bronchopulmonary dysplasia in extremely preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
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  9. Outbreak ofFrontiers in microbiology · 2026
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shalini SanthakumaranSection of Neonatal Medicine, Department of Medicine, Imperial College London, London, UK.
Yevgeniy StatnikovSection of Neonatal Medicine, Department of Medicine, Imperial College London, London, UK.
Daniel GraySection of Neonatal Medicine, Department of Medicine, Imperial College London, London, UK.
Cheryl BattersbySection of Neonatal Medicine, Department of Medicine, Imperial College London, London, UK.
Deborah AshbyImperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK.
Neena ModiSection of Neonatal Medicine, Department of Medicine, Imperial College London, London, UK.
Medicines for Neonates Investigator Group

Funding

Department of Health RP-PG-0707-10010
6 · The paper itself

Abstract

objectiveTo analyse survival trends and regional variation for very preterm infants admitted to neonatal care.

settingAll neonatal units in England. PATIENTS: Infants born at 22

methodsWe obtained data from the National Neonatal Research Database. We used logistic regression to model survival probability with birth weight, GA, sex, antenatal steroid exposure and multiple birth included in the risk adjustment model and calculated annualpercentage change (APC) for trends using joinpoint regression. We evaluated survival over a 20-year period for infants <26 weeks' GA using additional published data from the EPICure studies.

resultsWe identified 50 112 eligible infants. There was an increase in survival over 2008-2014 (2008: 88.0%; 2014: 91.3%; adjusted APC 0.46% (95% CI 0.30 to 0.62) p<0.001). The greatest improvement was at 22

conclusionsContinued national improvement in the survival of very preterm admissions masks important regional variation. Timely assessment of preterm survival is feasible using electronic records.

Indexed as

Birth WeightDatabases, FactualEnglandFemaleGestational AgeHumansInfantInfant MortalityInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Small for Gestational AgeInfant, Very Low Birth WeightLogistic ModelsMaleSurvival Ratedata collectionepidemiologyhealth services researchneonatology

Identifiers

PMID28883097
PMCPMC5916099

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.