ArticleScience (New York, N.Y.)2017
Behavioral time scale synaptic plasticity underlies CA1 place fields.
Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 381 papers.
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Who cites it
381 citing papers in PubMed.
- Instructive signals drive learning through behavioral timescale synaptic plasticity in the hippocampus and beyond.Current research in neurobiology · 2026Article
- Striatal endocannabinoids drive one-shot learning.Nature neuroscience · 2026Article
- Tuft Dendrite Spikes Are Accompanied by Selective Input From Distinct Functional Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Dentate gyrus interneurons modulate winner-take-all network dynamics in freely behaving mice.Neuron · 2026Article
- Calmodulin controls spatial and temporal specificity of calcium-induced calcium release.PLoS computational biology · 2026Article
- Top-down feedback in deep neural networks leads to functional differences during audiovisual integration.eLife · 2026Article
- Irregular and bursty neuronal firing extend spike-timing dependent plasticity window to behavioral timescales.iScience · 2026Article
- Distinct types of dendritic CaScience advances · 2026Article
- Neuromorphic Devices and Computing for Sensing, Memory, and Control.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Article
- Thalamocortical bursts encode reward contingencies and drive associative learning.Nature communications · 2026Article
- Subicular plateaus signal reward locations during goal-directed behavior.Cell reports · 2026Article
- Clustered inputs engage dendritic nonlinearities and calcium signaling to support efficient place-field formation in CA1 pyramidal neurons.Cell reports · 2026Article
- Article
- Place and behavioral modulation of hippocampal neurons during immobility.Nature communications · 2026Article
- NMDA receptor-dependent Hebbian plasticity refines hippocampal spatial representations during two-dimensional navigation learning.bioRxiv : the preprint server for biology · 2026Article
- The emergence of a novel CA1 spatial map requires direct entorhinal input.bioRxiv : the preprint server for biology · 2026Article
- Visual learning at fast and slow timescales is driven by distinct plasticity rules in primate inferotemporal cortex.Nature communications · 2026Article
- Article
- Learning Shapes the Energy Cost of Neural Tasks.bioRxiv : the preprint server for biology · 2026Article
321 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Learning is primarily mediated by activity-dependent modifications of synaptic strength within neuronal circuits. We discovered that place fields in hippocampal area CA1 are produced by a synaptic potentiation notably different from Hebbian plasticity. Place fields could be produced in vivo in a single trial by potentiation of input that arrived seconds before and after complex spiking. The potentiated synaptic input was not initially coincident with action potentials or depolarization. This rule, named behavioral time scale synaptic plasticity, abruptly modifies inputs that were neither causal nor close in time to postsynaptic activation. In slices, five pairings of subthreshold presynaptic activity and calcium (Ca
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.