Evidence map›Paper›PMID 28882993›Full record

ArticleScience (New York, N.Y.)2017

The condensin complex is a mechanochemical motor that translocates along DNA.

Tsuyoshi Terakawa, Shveta Bisht, Jorine M Eeftens, Cees Dekker, Christian H Haering, Eric C Greene

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Mitotic genome folding.The Journal of cell biology · 2025
    Review
  10. Article
  11. Article
  12. Nucleic Acids and Electrical Signals.Reviews of physiology, biochemistry and pharmacology · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Tsuyoshi TerakawaDepartment of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.ORCID 0000-0002-0151-1123
Shveta BishtCell Biology and Biophysics Unit, Structural and Computational Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID 0000-0002-5566-3472
Jorine M EeftensDepartment of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, Netherlands.ORCID 0000-0001-6784-9955
Cees DekkerDepartment of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, Netherlands. c.dekker@tudelft.nl christian.haering@embl.de ecg2108@cumc.columbia.edu.ORCID 0000-0001-6273-071X
Christian H HaeringCell Biology and Biophysics Unit, Structural and Computational Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. c.dekker@tudelft.nl christian.haering@embl.de ecg2108@cumc.columbia.edu.ORCID 0000-0001-8301-1722
Eric C GreeneDepartment of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA. c.dekker@tudelft.nl christian.haering@embl.de ecg2108@cumc.columbia.edu.ORCID 0000-0002-7387-824X

Funding

Protein purification instrumentation in support of single molecule studies of genome integrityR35GM118026 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GREENE, ERIC C · 2016 to 2025
$5.7M
European Research CouncilNIGMS NIH HHS R35 GM118026
6 · The paper itself

Abstract

Condensin plays crucial roles in chromosome organization and compaction, but the mechanistic basis for its functions remains obscure. We used single-molecule imaging to demonstrate that

Indexed as

Adenosine TriphosphatasesAdenosine TriphosphateChromosomes, FungalDNA-Binding ProteinsDNA, FungalMolecular Motor ProteinsMultiprotein ComplexesProtein BindingProtein TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSingle Molecule ImagingAdenosine TriphosphatasesAdenosine Triphosphatecondensin complexesDNA-Binding ProteinsDNA, FungalMolecular Motor ProteinsMultiprotein ComplexesSaccharomyces cerevisiae Proteins

Identifiers

PMID28882993
PMCPMC5862036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.