Evidence map›Paper›PMID 28882990›Full record

ArticleGenetics2017

Extended Synaptotagmin Localizes to Presynaptic ER and Promotes Neurotransmission and Synaptic Growth in

Koto Kikuma, Xiling Li, Daniel Kim, David Sutter, Dion K Dickman

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 88 citations in OpenAlex.

  1. Review
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  6. Nonionic signaling rapidly remodels postsynaptic DLG to induce retrograde homeostatic plasticity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Genetic dissection of theMolecular biology of the cell · 2025
    Article
  8. Article
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  12. DNA-Assisted Assays for Studying Lipid Transfer Between Membranes.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  13. The Endoplasmic Reticulum and Its Contacts: Emerging Roles in Axon Development, Neurotransmission, and Degeneration.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  14. Article
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  19. Biomarkers of Activity-Dependent Plasticity and Persistent Enhancement of Synaptic Transmission in Alzheimer Disease: A Review of the Current Status.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Review
  20. Rapid homeostatic modulation of transsynaptic nanocolumn rings.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Koto KikumaDepartment of Neurobiology, University of Southern California, Los Angeles, California 90089.
Xiling LiDepartment of Neurobiology, University of Southern California, Los Angeles, California 90089.
Daniel KimDepartment of Neurobiology, University of Southern California, Los Angeles, California 90089.
David SutterDepartment of Neurobiology, University of Southern California, Los Angeles, California 90089.
Dion K DickmanDepartment of Neurobiology, University of Southern California, Los Angeles, California 90089 dickman@usc.edu.
University of Southern California · US

Funding

Molecular Mechanisms Governing the Homeostatic Control of Synaptic StrengthR01NS091546 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DICKMAN, DION KAI · 2015 to 2024
$4.3M
NINDS NIH HHS R01 NS091546
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) is an extensive organelle in neurons with important roles at synapses including the regulation of cytosolic Ca

Indexed as

Neuronal OutgrowthSynaptic TransmissionAnimalsDrosophila melanogasterDrosophila ProteinsEndoplasmic ReticulumNeuromuscular JunctionPresynaptic TerminalsSynaptotagminsDrosophila ProteinsSynaptotagminsDrosophilaendoplasmic reticulumneuromuscular junctionsynapse

Identifiers

PMID28882990
PMCPMC5676231
OpenAlexW2753105126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.