Evidence map›Paper›PMID 28882952›Full record

ArticleIn vivo (Athens, Greece)

Comparing the Organs and Vasculature of the Head and Neck in Five Murine Species.

Min Jae Kim, Yoo Yeon Kim, Janet Ren Chao, Hae Sang Park, Jiwon Chang, Dawoon Oh, Jae Jun Lee, Tae Chun Kang, Jun-Gyo Suh, Jun Ho Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min Jae KimDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Yoo Yeon KimDepartment of Medical Genetics, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Janet Ren ChaoSchool of Medicine, George Washington University, Washington, DC, U.S.A.
Hae Sang ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Jiwon ChangDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Dawoon OhDepartment of Anesthesiology and Pain Medicine, Dongtan Sacred Heart Hospital, Hallym University, Dongtan, Republic of Korea.
Jae Jun LeeInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon, Republic of Korea.
Tae Chun KangDepartment of Anatomy and Neurobiology, College of Medicine, Hallym University, Chuncheon, Republic of Korea.
Jun-Gyo SuhDepartment of Medical Genetics, College of Medicine, Hallym University, Chuncheon, Republic of Korea jgsuh@hallym.ac.kr zoonox@nate.com.
Jun Ho LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Hallym University, Chuncheon, Republic of Korea jgsuh@hallym.ac.kr zoonox@nate.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe purpose of the present study was to delineate the cervical and facial vascular and associated anatomy in five murine species, and compare them for optimal use in research studies focused on understanding the pathology and treatment of diseases in humans. MATERIALS AND

methodsThe specific adult male animals examined were mice (C57BL/6J), rats (F344), mongolian gerbils (Merionesunguiculatus), hamsters (Syrian), and guinea pigs (Hartley). To stain the vasculature and organs, of the face and neck, each animal was systemically perfused using the vital stain, Trypan Blue. Following this step, the detailed anatomy of the head and neck could be easily visualized in all species.

resultsUnique morphological characteristics were demonstrated by comparing the five species, including symmetry of the common carotid origin bilaterally in the Mongolian Gerbil, a large submandibular gland in the hamster and an enlarged buccal branch in the Guinea Pig. In reviewing the anatomical details, this staining technique proves superior for direct surgical visualization and identification.

conclusionThe anatomical details provided through these five species atlas will help experimental researchers in the future to select the most appropriate animal model for specific laboratory studies aimed to improve our understanding and treatment of diseases in patients.

Indexed as

AnimalsBiopsyCricetinaeGerbillinaeGuinea PigsHeadMaleMiceMice, Inbred C57BLModels, AnatomicNeckRatsSpecies Specificityblood vesselsComparative anatomyneck anatomyneck dissectionrodentia

Identifiers

PMID28882952
PMCPMC5656859

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.