Evidence map›Paper›PMID 28882900›Full record

ArticleDiabetes2017

Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4.

Yangmeng Wang, Esther Paulo, Dongmei Wu, Yixuan Wu, Wendong Huang, Ajay Chawla, Biao Wang

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

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  15. Elucidation of the Mechanisms and Molecular Targets ofBioMed research international · 2020
    Article
  16. [Time-sequential expression of lnc AK079912 during adipose tissue development and browning in mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yangmeng WangDepartment of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA.
Esther PauloDepartment of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA.
Dongmei WuDepartment of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA.
Yixuan WuDepartment of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA.
Wendong HuangDepartment of Diabetes Complications and Metabolism, Beckman Research Institute of City of Hope, Duarte, CA.
Ajay ChawlaDepartment of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA.
Biao WangDepartment of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA biao.wang@ucsf.edu.ORCID 0000-0001-8514-3825
University of California, San Francisco · USCity of Hope · US

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRUMMEL, MATTHEW F · 2003 to 2019
$21.8M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
MiRNAs in hepatocellular carcinoma development and treatmentR01CA139158 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI HUANG, WENDONG, YU, HUA E · 2011 to 2021
$3.7M
Innate Immune Mechanisms of ThermogenesisR01DK094641 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, BIAO · 2011 to 2019
$3.5M
Transcriptional control in brown and beige adipocytesR01DK105175 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, BIAO · 2015 to 2019
$1.8M
Myeloid Cell Functions in Obesity and Diabetes.R01DK101064 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAWLA, AJAY · 2015 to 2018
$1.6M
NCI NIH HHS R01 CA139158NIDDK NIH HHS P30 DK063720NIDDK NIH HHS P30 DK098722NIDDK NIH HHS R01 DK094641NIDDK NIH HHS R01 DK101064NIDDK NIH HHS R01 DK105175
6 · The paper itself

Abstract

Uncoupling protein 1

Indexed as

Adipocytes, BeigeAMP-Activated Protein KinasesAnimalsCold TemperatureDiet, High-FatFemaleHistone DeacetylasesMaleMiceMice, Inbred C57BLProtein Serine-Threonine KinasesThermogenesisUncoupling Protein 1AMP-Activated Protein KinasesHdac5 protein, mouseHistone DeacetylasesProtein Serine-Threonine KinasesStk11 protein, mouseUcp1 protein, mouseUncoupling Protein 1

Identifiers

PMID28882900
PMCPMC5697944
OpenAlexW2752534656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.