ArticleThe Journal of biological chemistry2017
C-terminal phosphorylation of Na
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Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Targeting Arrhythmogenic Late Sodium Current by FHF1Circulation research · 2026Article
- The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding.The Journal of clinical investigation · 2025Article
- Differential Inhibition by Cenobamate of Canonical Human Nav1.5 Ion Channels and Several Point Mutants.International journal of molecular sciences · 2025Article
- Effects of rumen-protected lysine on antler growth performance, fecal bacterial community, and blood gene expression in sika deer.Frontiers in veterinary science · 2025Article
- Characterization of novel arrhythmogenic patterns arising secondary to heterogeneous expression and activation of Nav1.8.Frontiers in cardiovascular medicine · 2025Article
- Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse.The Journal of general physiology · 2023Article
- Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors.The Journal of general physiology · 2023Article
- Fibroblast growth factor 13-mediated regulation of medium spiny neuron excitability and cocaine self-administration.Frontiers in neuroscience · 2023Article
- Genomic and Non-Genomic Regulatory Mechanisms of the Cardiac Sodium Channel in Cardiac Arrhythmias.International journal of molecular sciences · 2022Review
- Transcriptional profiles of genes related to electrophysiological function in Scn5aPhysiological reports · 2021Article
- Review
- Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation sites.The Journal of general physiology · 2021Article
- Genetic Characteristics and Transcriptional Regulation of Sodium Channel Related Genes in Chinese Patients With Brugada Syndrome.Frontiers in cardiovascular medicine · 2021Article
- Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding-deficient channels.JCI insight · 2020Article
- Development of a Bioinformatics Framework for Identification and Validation of Genomic Biomarkers and Key Immunopathology Processes and Controllers in Infectious and Non-infectious Severe Inflammatory Response Syndrome.Frontiers in immunology · 2020Article
- "Heart Oddity": Intrinsically Reduced Excitability in the Right Ventricle Requires Compensation by Regionally Specific Stress Kinase Function.Frontiers in physiology · 2020Review
- Conduction in the right and left ventricle is differentially regulated by protein kinases and phosphatases: implications for arrhythmogenesis.American journal of physiology. Heart and circulatory physiology · 2019Article
- Phosphorylation of cardiac voltage-gated sodium channel: Potential players with multiple dimensions.Acta physiologica (Oxford, England) · 2019Review
- Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity.The Journal of biological chemistryArticle
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 4 countries.
Sophie BurelFrom the l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, Nantes 44007, France.
Fabien C CoyanFrom the l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, Nantes 44007, France.
Maxime LorenziniFrom the l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, Nantes 44007, France.
Matthew R Meyerthe Departments of Medicine.
Cheryl F Lichtithe Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555.
Joan H Brownthe Department of Pharmacology, University of California at San Diego, La Jolla, California 92093-0636, and.
Gildas LoussouarnFrom the l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, Nantes 44007, France.
Flavien CharpentierFrom the l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, Nantes 44007, France.
Jeanne M NerbonneDevelopmental Biology.
R Reid TownsendInternal Medicine, and.
Lars S Maierthe Department of Internal Medicine II, University Heart Center, University Hospital Regensburg, D-93042 Regensburg, Germany.
Céline MarionneauFrom the l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, Nantes 44007, France, celine.marionneau@univ-nantes.fr.
Institut du Thorax · FRCentre National de la Recherche Scientifique · FRInserm · FRInstitute of Developmental Physiology · RUThe University of Texas Medical Branch at Galveston · USUniversity Hospital Regensburg · DEUniversity of California, San Diego · USWashington University in St. Louis · US
Funding
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8MWashington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4MProgram AdministrationP01HL080101 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERS, DONALD M · 2006 to 2015
$23.4MTrainingP41GM103422 · NIGMS · WASHINGTON UNIVERSITY · PI YARASHESKI, KEVIN E · 2012 to 2019
$12.0MION CHANNEL REGULATION AND MODULATION IN CARDIAC MUSCLER01HL034161 · NHLBI · WASHINGTON UNIVERSITY · PI NERBONNE, JEANNE M. · 1986 to 2015
$4.6MA Biomedical Mass Spectrometry Resource: Ongoing Driving Biomedical ProjectsR24GM136766 · NIGMS · WASHINGTON UNIVERSITY · PI GROSS, MICHAEL L · 2020 to 2022
$2.3MNCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NHLBI NIH HHS P01 HL080101NHLBI NIH HHS R01 HL034161NIGMS NIH HHS P41 GM103422NIGMS NIH HHS R24 GM136766
Abstract
Voltage-gated Na
Indexed as
Ion Channel GatingAmino Acid SubstitutionAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Fibroblast Growth FactorsHeart FailureHEK293 CellsHumansMiceMice, TransgenicMutation, MissenseNAV1.5 Voltage-Gated Sodium ChannelPhosphorylationCalcium-Calmodulin-Dependent Protein Kinase Type 2fibroblast growth factor 13Fibroblast Growth FactorsNAV1.5 Voltage-Gated Sodium ChannelSCN5A protein, humanScn5a protein, mouseCa2+/calmodulin-dependent protein kinase II (CaMKII)calmodulin (CaM)channel inactivationFGF13heartNav1.5phosphoproteomicsphosphorylationsodium channel
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Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.