Autoimmune disease variants regulate

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. GLRB variants regulate nearby gene expression in human brain tissues.Scientific reports · 2017
   Pooled it
2. The gasdermin family: from pyroptosis mechanisms to therapeutic targets.Signal transduction and targeted therapy · 2026
   Review
3. Advances in the research of gasdermin-dependent pyroptosis mechanisms and therapeutic targets in inflammatory diseases.Apoptosis : an international journal on programmed cell death · 2026
   Review
4. Pyroptosis Regulated by N6-Methyladenosine Modification: Implications for Pyroptosis-Related Disease Therapy.Journal of innate immunity · 2026
   Review
5. GSDMD-mediated pyroptosis: molecular mechanisms, diseases and therapeutic targets.Molecular biomedicine · 2025
   Review
6. Pyroptosis: Induction and inhibition strategies for immunotherapy of diseases.Acta pharmaceutica Sinica. B · 2024
   Review
7. The gasdermin family: emerging therapeutic targets in diseases.Signal transduction and targeted therapy · 2024
   Review
8. To die or not to die: Gasdermins in intestinal health and disease.Seminars in immunology · 2024
   Review
9. From gene identifications to therapeutic targets for asthma: Focus on great potentials ofChinese medical journal pulmonary and critical care medicine · 2023
   Review
10. Gasdermins and pyroptosis in the kidney.Nature reviews. Nephrology · 2023
    Review
11. The gasdermins: a pore-forming protein family expressed in the epidermis.Frontiers in immunology · 2023
    Review
12. Pyroptosis: Role and Mechanisms in Cardiovascular Disease.Frontiers in cardiovascular medicine · 2022
    Review
13. Modulation of Autoimmune and Autoinflammatory Diseases by Gasdermins.Frontiers in immunology · 2022
    Review
14. Gasdermins in Innate Host Defense AgainstFrontiers in immunology · 2022
    Review
15. Pyroptosis, metabolism, and tumor immune microenvironment.Clinical and translational medicine · 2021
    Review
16. Channelling inflammation: gasdermins in physiology and disease.Nature reviews. Drug discovery · 2021
    Review
17. Chromosome 17q12-21 Variants Are Associated with Multiple Wheezing Phenotypes in Childhood.American journal of respiratory and critical care medicine · 2021
    Article
18. rs1990622 variant associates with Alzheimer's disease and regulates TMEM106B expression in human brain tissues.BMC medicine · 2021
    Article
19. Pyroptosis, a New Breakthrough in Cancer Treatment.Frontiers in oncology · 2021
    Review
20. Biological Functions of Gasdermins in Cancer: From Molecular Mechanisms to Therapeutic Potential.Frontiers in cell and developmental biology · 2021
    Review

Corrections and comments

• Commented on by
  Reply to HU et al.: On the interpretation of gasdermin-B expression quantitative trait loci data.2017
• Comment on
  Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein.2017

Authors and funding

5 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as