Evidence map›Paper›PMID 28882861›Full record

ArticleAJNR. American journal of neuroradiology2017

Real-Time Motor Cortex Mapping for the Safe Resection of Glioma: An Intraoperative Resting-State fMRI Study.

T-M Qiu, F-Y Gong, X Gong, J-S Wu, C-P Lin, B B Biswal, D-X Zhuang, C-J Yao, X-L Zhang, J-F Lu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  6. Resting-state functional MRI for motor cortex mapping in childhood-onset focal epilepsy.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

T-M QiuFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-1089-4717
F-Y GongFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-4889-3867
X GongFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-8824-2407
J-S WuFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-7854-9798
C-P LinCenter for Computational Systems Biology (C.-p.L.), Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-6848-8776
B B BiswalDepartment of Biomedical Engineering (B.B.B.), New Jersey Institute of Technology, Newark, New Jersey.ORCID http://orcid.org/0000-0002-3710-3500
D-X ZhuangFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China lfzhouc@126.com ernestzdx@163.com.ORCID http://orcid.org/0000-0002-4964-6529
C-J YaoFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-1392-5275
X-L ZhangFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-6228-8527
J-F LuFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0003-1090-2959
F-P ZhuFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-5976-8861
Y MaoFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0001-7350-5518
L-F ZhouFrom the Department of Neurological Surgery (T.-m.Q., F.-y.G., X.G., J.-s.W., D.-x.Z., C.-j.Y., X.-l.Z., J.-f.L., F.-p.Z., Y.M., L.-f.Z.), Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China lfzhouc@126.com ernestzdx@163.com.ORCID http://orcid.org/0000-0002-0675-7720

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeResting-state functional MR imaging has been used for motor mapping in presurgical planning but never used intraoperatively. This study aimed to investigate the feasibility of applying intraoperative resting-state functional MR imaging for the safe resection of gliomas using real-time motor cortex mapping during an operation. MATERIALS AND

methodsUsing interventional MR imaging, we conducted preoperative and intraoperative resting-state intrinsic functional connectivity analyses of the motor cortex in 30 patients with brain tumors. Factors that may influence intraoperative imaging quality, including anesthesia type (general or awake anesthesia) and tumor cavity (filled with normal saline or not), were studied to investigate image quality. Additionally, direct cortical stimulation was used to validate the accuracy of intraoperative resting-state fMRI in mapping the motor cortex.

resultsPreoperative and intraoperative resting-state fMRI scans were acquired for all patients. Fourteen patients who successfully completed both sufficient intraoperative resting-state fMRI and direct cortical stimulation were used for further analysis of sensitivity and specificity. Compared with those subjected to direct cortical stimulation, the sensitivity and specificity of intraoperative resting-state fMRI in localizing the motor area were 61.7% and 93.7%, respectively. The image quality of intraoperative resting-state fMRI was better when the tumor cavity was filled with normal saline (

conclusionsThis study demonstrates the feasibility of using intraoperative resting-state fMRI for real-time localization of functional areas during a neurologic operation. The findings suggest that using intraoperative resting-state fMRI can avoid the risk of intraoperative seizures due to direct cortical stimulation and may provide neurosurgeons with valuable information to facilitate the safe resection of gliomas.

Indexed as

AdultAgedBrain MappingBrain NeoplasmsFemaleGliomaHumansIntraoperative Neurophysiological MonitoringMagnetic Resonance ImagingMaleMiddle AgedMotor CortexSensitivity and SpecificityYoung Adult

Identifiers

PMID28882861
PMCPMC7963570

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.