Evidence map›Paper›PMID 28882854›Full record

ArticleGenes & development2017

Mutation of

Jing Wang, Todd Blevins, Ram Podicheti, Jeremy R Haag, Ek Han Tan, Feng Wang, Craig S Pikaard

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. RNA-directed DNA Methylation.PLoS genetics · 2020
    Article
  14. Article
  15. Review
  16. Article
  17. Condensin action and compaction.Current genetics · 2019
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jing WangDepartment of Biology, Indiana University, Bloomington, Indiana, 47405, USA.
Todd BlevinsDepartment of Biology, Indiana University, Bloomington, Indiana, 47405, USA.
Ram PodichetiCenter for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, 47405, USA.
Jeremy R Haag
Ek Han Tan
Feng WangDepartment of Biology, Indiana University, Bloomington, Indiana, 47405, USA.
Craig S PikaardDepartment of Biology, Indiana University, Bloomington, Indiana, 47405, USA.ORCID 0000-0001-8204-7459
Indiana University Bloomington · USHoward Hughes Medical Institute · USMonsanto (United States) · USUniversity of Maine · US

Funding

Roles of RNA Polymerases IV and V in siRNA-mediated gene silencingR01GM077590 · NIGMS · WASHINGTON UNIVERSITY · PI PIKAARD, CRAIG STUART · 2006 to 2020
$3.5M
NIGMS NIH HHS R01 GM077590
6 · The paper itself

Abstract

In eukaryotes, transcriptionally inactive loci are enriched within highly condensed heterochromatin. In plants, as in mammals, the DNA of heterochromatin is densely methylated and wrapped by histones displaying a characteristic subset of post-translational modifications. Growing evidence indicates that these chromatin modifications are not sufficient for silencing. Instead, they are prerequisites for further assembly of higher-order chromatin structures that are refractory to transcription but not fully understood. We show that silencing of transposons in the pericentromeric heterochromatin of

Indexed as

Gene Expression Regulation, PlantAdenosine TriphosphatasesArabidopsisArabidopsis ProteinsCentrosomeChromatinDNA-Binding ProteinsDNA MethylationDNA RepairDNA Transposable ElementsGene SilencingGenome-Wide Association StudyGenotyping TechniquesHeterochromatinHistonesMethyltransferasesAdenosine TriphosphatasesArabidopsis ProteinsATXR5 protein, ArabidopsisATXR6 protein, ArabidopsisCAP-C protein, ArabidopsisChromatincondensin complexesDNA-Binding ProteinsDNA Transposable ElementsHeterochromatinHistonesMethyltransferasesMultiprotein Complexeschromosome condensationDNA methylationepigenetic regulationgene silencingheterochromatin formationSMC proteins

Identifiers

PMID28882854
PMCPMC5630024
OpenAlexW2751171053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.