Evidence map›Paper›PMID 28882679›Full record

ArticleContraception2017

Measuring oral contraceptive adherence using self-report versus pharmacy claims data.

Hallie N Nelson, Sonya Borrero, Erik Lehman, Diana L Velott, Cynthia H Chuang

Open access · greenAbstract read
In one paragraph

Article in Contraception, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Family Planning Reminder Systems: An Updated Systematic Review.American journal of preventive medicine · 2018
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hallie N NelsonPenn State College of Medicine. Electronic address: hnelson1@pennstatehealth.psu.edu.
Sonya BorreroDivision of General Internal Medicine, University of Pittsburgh; Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System.
Erik LehmanDepartment of Public Health Sciences, Penn State College of Medicine.
Diana L VelottDepartment of Public Health Sciences, Penn State College of Medicine.
Cynthia H ChuangDivision of General Internal Medicine, Penn State College of Medicine; Department of Public Health Sciences, Penn State College of Medicine.
Pennsylvania State University · USVA Pittsburgh Healthcare System · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014
6 · The paper itself

Abstract

objectiveProportion of Days Covered (PDC) is a measure of medication adherence that uses prescription claims data to describe the proportion of days that the patient possessed medication. The objective of this study is to compare PDC and self-report as measures of oral contraceptive pills (OCPs) adherence and to identify individual-level predictors of adherence. STUDY

designIn a sample of 384 OCP users, self-report was compared with PDC as measures of adherence over the past 3 months. Patient-level variables were examined for associations with adherence using multivariable logistic regression models.

resultsHigh adherence, defined as missing ≤1 pill per month, was 76%, 68% and 54% as measured by self-report, PDC and both measures, respectively. Younger women (ages 18-25 and 26-33 years) were significantly less likely to have high adherence on both measures than women in the 34-40 age group [adjusted odds ratio (OR) 0.20, 95% confidence interval (CI) 0.08-0.51 and adjusted OR 0.26, 95% CI 0.11-0.62, respectively). Other predictors of high adherence on both self-report and PDC measures included being in a relationship (adjusted OR 2.30, 95% CI 1.14-4.64, compared with unpartnered women), Protestant religion (adjusted OR 2.08, 95% CI 1.07-4.06, compared with women with no religious affiliation) and higher contraceptive self-efficacy (adjusted OR 1.63, 95% CI 1.03-2.58).

conclusionPDC derived from pharmacy claims, or a combination of PDC and self-report measures, may be an alternative to self-report alone for measuring OCP adherence. IMPLICATIONS: PDC may be a potential tool for measuring women's adherence to OCPs and should be validated in future studies.

Indexed as

ContraceptionMedication AdherenceAdolescentAdultAge FactorsContraceptives, Oral, HormonalHumansPharmaceutical ServicesReligionSelf EfficacySelf ReportYoung AdultContraceptives, Oral, HormonalBirth control pillsProportion days covered

Identifiers

PMID28882679
PMCPMC6540974
OpenAlexW2751849890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.