Evidence map›Paper›PMID 28882454›Full record

ReviewTrends in immunology2017

Understanding Immunity through the Lens of Disease Ecology.

Stephen M Hedrick

Abstract readReview
In one paragraph

Review in Trends in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. The contribution of host cell-directed vs. parasite-directed immunity to the disease and dynamics of malaria infections.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  5. Ferreting out viral pathogenesis.Nature microbiology · 2019
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stephen M HedrickDepartments of Molecular Biology and Cellular and Molecular Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. Electronic address: shedrick@ucsd.edu.
University of California, San Diego · US

Funding

Mutagenic chain reaction-facilitated immunotherapyR01AI131081 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BIER, ETHAN, GOLDRATH, ANANDA W · 2016 to 2020
$3.3M
A molecular basis for control of T cell memoryR01AI103440 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HEDRICK, STEPHEN M · 2013 to 2017
$2.3M
NIAID NIH HHS R01 AI103440NIAID NIH HHS R01 AI131081
6 · The paper itself

Abstract

As we describe the immune system in ever more exquisite detail, we might find that no matter how successful, this approach will not be sufficient to understand the spread of infectious agents, their susceptibility to vaccine therapy, and human disease resistance. Compared with the strict reductionism practiced as a means of characterizing most biological processes, I propose that the progression and outcome of disease-causing host-parasite interactions will be more clearly understood through a focus on disease ecology.

Indexed as

ImmunityModels, ImmunologicalAnimalsBiological EvolutionCoinfectionDisease Transmission, InfectiousHost-Pathogen InteractionsHumansInfectionsVirulenceVirulence FactorsZoonosesVirulence Factors

Identifiers

PMID28882454
PMCPMC5711578
OpenAlexW2753548821

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.