Evidence map›Paper›PMID 28882442›Full record

ArticleVaccine2017

Polio immunity and the impact of mass immunization campaigns in the Democratic Republic of the Congo.

Arend Voorman, Nicole A Hoff, Reena H Doshi, Vivian Alfonso, Patrick Mukadi, Jean-Jacques Muyembe-Tamfum, Emile Okitolonda Wemakoy, Ado Bwaka, William Weldon, Sue Gerber and 1 more

Abstract read
In one paragraph

Article in Vaccine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Arend VoormanThe Bill and Melinda Gates Foundation, Seattle 98109, USA.
Nicole A HoffDepartment of Epidemiology, University of California, Los Angeles 90095, USA.
Reena H DoshiDepartment of Epidemiology, University of California, Los Angeles 90095, USA.
Vivian AlfonsoDepartment of Epidemiology, University of California, Los Angeles 90095, USA.
Patrick MukadiNational Institute for Biomedical Research (INRB), Kinshasa, The Democratic Republic of the Congo.
Jean-Jacques Muyembe-TamfumNational Institute for Biomedical Research (INRB), Kinshasa, The Democratic Republic of the Congo.
Emile Okitolonda WemakoyKinshasa School of Public Health, Kinshasa, The Democratic Republic of the Congo.
Ado BwakaExpanded Programme on Immunization, McKing Consulting, Kinshasa, The Democratic Republic of the Congo.
William WeldonDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta 30329, USA.
Sue GerberThe Bill and Melinda Gates Foundation, Seattle 98109, USA.
Anne W RimoinDepartment of Epidemiology, University of California, Los Angeles 90095, USA. Electronic address: arimoin@ucla.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn order to prevent outbreaks from wild and vaccine-derived poliovirus, maintenance of population immunity in non-endemic countries is critical.

methodsWe estimated population seroprevalence using dried blood spots collected from 4893 children 6-59months olds in the 2013-2014 Demographic and Health Survey in the Democratic Republic of the Congo (DRC).

resultsPopulation immunity was 81%, 90%, and 70% for poliovirus types 1, 2, and 3, respectively. Among 6-59-month-old children, 78% reported at least one dose of polio in routine immunization, while only 15% had three doses documented on vaccination cards. All children in the study had been eligible for at least two trivalent oral polio vaccine campaigns at the time of enrollment; additional immunization campaigns seroconverted 5.0%, 14%, and 5.5% of non-immune children per-campaign for types 1, 2, and 3, respectively, averaged over relevant campaigns for each serotype.

conclusionsOverall polio immunity was high at the time of the study, though pockets of low immunity cannot be ruled out. The DRC still relies on supplementary immunization campaigns, and this report stresses the importance of the quality and coverage of those campaigns over their quantity, as well as the importance of routine immunization.

Indexed as

Child, PreschoolDemocratic Republic of the CongoDisease OutbreaksFemaleHumansInfantMaleMass VaccinationPoliomyelitisPoliovirusPoliovirus Vaccine, OralSeroepidemiologic StudiesVaccinationPoliovirus Vaccine, OralDemocratic Republic of the CongoImmunizationMass vaccinationPoliomyelitisSeroprevalence

Identifiers

PMID28882442
PMCPMC5628608

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.