Evidence map›Paper›PMID 28882191›Full record

ArticleActa neuropathologica communications2017

Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling.

Minesh Kapadia, Dunja Bijelić, Hui Zhao, Donglai Ma, Ljudmila Stojanovich, Milena Milošević, Pavle Andjus, Boris Šakić

Open access · goldAbstract read
In one paragraph

Article in Acta neuropathologica communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. The MRL Model: A Valuable Tool in Studies of Autoimmunity-Brain Interactions.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Minesh KapadiaDepartment of Psychiatry and Behavioral Neurosciences, McMaster University, Psychology Building Rm. 303, 1280 Main St., West Hamilton, ON, L8S 4K1, Canada.
Dunja BijelićFaculty of Biology, University of Belgrade, Belgrade, Serbia.
Hui ZhaoDepartment of Psychiatry and Behavioral Neurosciences, McMaster University, Psychology Building Rm. 303, 1280 Main St., West Hamilton, ON, L8S 4K1, Canada.
Donglai MaDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
Ljudmila StojanovichInternal Medicine, "Bezanijska Kosa", University Medical Center, Belgrade, Serbia.
Milena MiloševićFaculty of Biology, University of Belgrade, Belgrade, Serbia.
Pavle AndjusFaculty of Biology, University of Belgrade, Belgrade, Serbia.
Boris ŠakićDepartment of Psychiatry and Behavioral Neurosciences, McMaster University, Psychology Building Rm. 303, 1280 Main St., West Hamilton, ON, L8S 4K1, Canada. sakic@mcmaster.ca.ORCID 0000-0002-0531-4872
McMaster University · CAUniversity of Belgrade · RSUniversity Hospital Medical Center Bezanijska kosa · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a potentially fatal autoimmune disease that is often accompanied by brain atrophy and diverse neuropsychiatric manifestations of unknown origin. More recently, it was observed that cerebrospinal fluid (CSF) from patients and lupus-prone mice can be neurotoxic and that acute administration of specific brain-reactive autoantibodies (BRAs) can induce deficits in isolated behavioral tasks. Given the chronic and complex nature of CNS SLE, the current study examines broad behavioral performance and neuronal Ca

Indexed as

AgedAnimalsAutoantibodiesBehavior, AnimalBrainCalcium SignalingCells, CulturedDepressionDisease Models, AnimalFemaleHumansInfusions, IntraventricularLearning DisabilitiesLupus Erythematosus, SystemicMaleMemory DisordersAutoantibodiesAnti-NMDA receptorAnti-ribosomal PAnti-α-tubulinAutoimmunityBrain-reactive autoantibodiesCerebrospinal fluidCNS SLE

Identifiers

PMID28882191
PMCPMC5590168
OpenAlexW2751298042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.