Evidence map›Paper›PMID 28882067›Full record

ReviewAIDS research and human retroviruses2017

Differentiating Immune Cell Targets in Gut-Associated Lymphoid Tissue for HIV Cure.

Shahzada Khan, Sushama Telwatte, Martin Trapecar, Steven Yukl, Shomyseh Sanjabi

Open access · bronzeAbstract readReview
In one paragraph

Review in AIDS research and human retroviruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shahzada Khan1 Gladstone Institute of Virology and Immunology, Gladstone Institutes, San Francisco, California.
Sushama Telwatte2 San Francisco VA Health Care System and University of California, San Francisco (UCSF), San Francisco, California.
Martin Trapecar1 Gladstone Institute of Virology and Immunology, Gladstone Institutes, San Francisco, California.
Steven Yukl2 San Francisco VA Health Care System and University of California, San Francisco (UCSF), San Francisco, California.
Shomyseh Sanjabi1 Gladstone Institute of Virology and Immunology, Gladstone Institutes, San Francisco, California.
Gladstone Institutes · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Characterizing HIV latent reservoir in vivoDP2AI112244 · NIAID · J. DAVID GLADSTONE INSTITUTES · PI SANJABI, SHOMYSEH · 2013 to 2013
$2.8M
Investigating Mechanisms of HIV Persistence in the GutR01DK108349 · NIDDK · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI YUKL, STEVEN A · 2015 to 2019
$2.2M
Understanding HIV latency reversal and clearance of infected cells in vivoR01AI132128 · NIAID · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI WONG, JOSEPH K, YUKL, STEVEN A · 2017 to 2021
$1.9M
NIAID NIH HHS DP2 AI112244NIAID NIH HHS P30 AI027763NIAID NIH HHS R01 AI132128NIDDK NIH HHS R01 DK108349
6 · The paper itself

Abstract

The single greatest challenge to an HIV cure is the persistence of latently infected cells containing inducible, replication-competent proviral genomes, which constitute only a small fraction of total or infected cells in the body. Although resting CD4

Indexed as

Anti-HIV AgentsCD4-Positive T-LymphocytesHIV-1HIV InfectionsHumansIntestinal MucosaLymphoid TissueTh17 CellsTh1 CellsT-Lymphocytes, RegulatoryVirus LatencyVirus ReplicationAnti-HIV Agentsgastrointestinal tractHIV curelatencymucosareservoirT cells

Identifiers

PMID28882067
PMCPMC5685216
OpenAlexW2753590007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.