Evidence map›Paper›PMID 28881843›Full record

ArticleOncotarget2017

Dynamic changes in serum cytokine levels and their clinical significance in predicting acute GVHD.

Chunyan Zhang, Wenrong Huang, Pengjun Zhang, Qingyi Zhang, Guanghong Guo, Feng Gu, Hua Yang, Yurong Wang, Xueliang Huang, Qian Jia and 1 more

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The level of Tim-3+CD8+ T cells can serve as a potential marker for evaluating the severity of acute graft-versus-host disease after haplo-PBSCT.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  6. Biosensors for inflammation as a strategy to engineer regulatory T cells for cell therapy.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Review
  8. Article
  9. Prevention and Treatment of Acute Graft-versus-Host Disease in Children, Adolescents, and Young Adults.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chunyan ZhangCore Laboratory of Translational Medicine, State Key Laboratory of Kidney Disease, Chinese People's Liberation Army General Hospital, Beijing, China.
Wenrong HuangDepartment of Hematology, Chinese People's Liberation Army General Hospital, Beijing, China.
Pengjun ZhangCore Laboratory of Translational Medicine, State Key Laboratory of Kidney Disease, Chinese People's Liberation Army General Hospital, Beijing, China.
Qingyi ZhangDepartment of Hematology, Air Force General Hospital, People's Liberation Army, Beijing, China.
Guanghong GuoDepartment of Clinical Biochemistry, Chinese People's Liberation Army General Hospital, Beijing, China.
Feng GuDepartment of Clinical Biochemistry, Chinese People's Liberation Army General Hospital, Beijing, China.
Hua YangDepartment of Hematology, Chinese People's Liberation Army General Hospital, Beijing, China.
Yurong WangCore Laboratory of Translational Medicine, State Key Laboratory of Kidney Disease, Chinese People's Liberation Army General Hospital, Beijing, China.
Xueliang HuangCore Laboratory of Translational Medicine, State Key Laboratory of Kidney Disease, Chinese People's Liberation Army General Hospital, Beijing, China.
Qian JiaCore Laboratory of Translational Medicine, State Key Laboratory of Kidney Disease, Chinese People's Liberation Army General Hospital, Beijing, China.
Yaping TianCore Laboratory of Translational Medicine, State Key Laboratory of Kidney Disease, Chinese People's Liberation Army General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the clinical significance of cytokines and biochemical tests in acute graft-versus-host disease (aGVHD), we detected the concentrations of 8 cytokines and 19 conventional biochemical markers in the sera of aGVHD and non-GVHD patients throughout the process of allogeneic hematopoietic stem cell transplantation and the onset of aGVHD. Predictive models were then established using the 27 indices, and models were verified by a prospective trial. The 27 indices showed significant differences between aGVHD patients and non-GVHD control subjects (two-tailed

Indexed as

aGVHD predictionallogeneic hematopoietic stem cell transplantationbiochemical indicescytokinesgraft-versus-host disease

Identifiers

PMID28881843
PMCPMC5581142

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.