ArticleOncotarget2017
A vitamin D receptor agonist converts CD4+ T cells to Foxp3+ regulatory T cells in patients with ulcerative colitis.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Survivin Impairs the Apoptotic Machinery in CD4+ T Cells of Patients with Ulcerative Colitis.Journal of innate immunity · 2020Trial
- Expansion of the CD4The Journal of allergy and clinical immunology · 2020Trial
- Review
- Vitamin D treatment distinctly modulates cytokine production by peripheral blood mononuclear cells among patients with chronic cardiac and indeterminate clinical forms of Chagas disease.Immunity, inflammation and disease · 2024Article
- Biomaterial-enhanced treg cell immunotherapy: A promising approach for transplant medicine and autoimmune disease treatment.Bioactive materials · 2024Review
- Group AScience immunology · 2023Article
- EB1089 promotes the expression of vitamin D receptor in the intestinal epithelial cell line HT-29 and reduces lipopolysaccharide-induced inflammatory response.Annals of translational medicine · 2022Article
- Tissue Nutrient Environments and Their Effect on Regulatory T Cell Biology.Frontiers in immunology · 2021Review
- Article
- Medical Treatment Can Unintentionally Alter the Regulatory T-Cell Compartment in Patients with Widespread Pathophysiologic Conditions.The American journal of pathology · 2020Review
- Immunohistochemical expression of vitamin D receptor and forkhead box P3 in classic Hodgkin lymphoma: correlation with clinical and pathologic findings.BMC cancer · 2020Article
- Metabolic Optimisation of Regulatory T Cells in Transplantation.Frontiers in immunology · 2020Review
- Emerging role of lncRNAs in the normal and diseased intestinal barrier.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018Review
- The role of vitamin D testing and replacement in fibromyalgia: a systematic literature review.BMC rheumatology · 2018Article
- Regulation of Microbiota by Vitamin D Receptor: A Nuclear Weapon in Metabolic Diseases.Nuclear receptor research · 2018Article
- Emerging Functions of Regulatory T Cells in Tissue Homeostasis.Frontiers in immunology · 2018Review
- Knockdown of NCOA2 Inhibits the Growth and Progression of Gastric Cancer by Affecting the Wnt Signaling Pathway-Related Protein Expression.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the pathological features of ulcerative colitis (UC) is the dysfunction of immune regulatory T cells (Treg cells); the pathogenesis is unclear and needs to be further investigated. Vitamin D has immune regulatory functions. This study tests a hypothesis that vitamin D receptor (VDR) regulates Treg cell differentiation. Peripheral blood samples were collected from UC patients and healthy subjects. The correlation between VDR expression and T helper (Th)2 cell differentiation in peripheral CD4
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.