Evidence map›Paper›PMID 28881762›Full record

ArticleOncotarget2017

Erectile dysfunction and the risk of prostate cancer.

Wei-Yu Lin, Ying-Hsu Chang, Cheng-Li Lin, Chia-Hung Kao, Hsi-Chin Wu

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prostate Cancer in Primary Care.Advances in therapy · 2018
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Wei-Yu LinDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital, Gia-Yi, Taiwan.
Ying-Hsu ChangDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital, LinKo, Taiwan.
Cheng-Li LinManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
Chia-Hung KaoGraduate Institute of Clinical Medical Science, College of Medicine, China Medical University, Taichung, Taiwan.
Hsi-Chin WuDepartment of Urology, China Medical University Hospital, Taichung, Taiwan.
China Medical University Hospital · TWChang Gung Memorial Hospital · TWChang Gung University of Science and Technology · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProstate cancer (PCa) is the most commonly diagnosed malignancy and the third leading cause of cancer death among men in developed countries. Because some risk factors are common between erectile dysfunction (ED) and PCa, we investigated the association between ED and subsequent PCa.

methodsThis nationwide population-based cohort study used data from the Taiwan National Health Insurance Research Database for the period 2000-2010. We identified patients newly diagnosed with ED by using codes from the International Classification of Diseases, Ninth Revision, Clinical Modification.

resultsIn total, 5858 and 23432 patients were enrolled in the ED and non-ED cohorts, respectively. After adjustment for age, sex, and comorbidities, the overall incidence densities of PCa were significantly higher in the ED cohort than in the non-ED cohort, with an adjusted hazard ratio (aHR) of 1.19. The age-specific relative risk of PCa was significantly higher for all age groups in the ED cohort than in the non-ED cohort. Compared with patients without ED, those with organic ED had a 1.27-fold higher risk of PCa.

conclusionED is a harbinger of PCa in some men. Physicians should consider the possibility of occult PCa in patients with ED regardless of age and comorbidities.

Indexed as

Cohort studyerectile dysfunction (ED)malignancyNational Health Insurance Research DatabaseProstate cancer (PCa)

Identifiers

PMID28881762
PMCPMC5581061
OpenAlexW2606852825

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.