Evidence map›Paper›PMID 28881623›Full record

ArticleOncotarget2017

Peptide-based PET imaging of the tumor restricted IL13RA2 biomarker.

Kiran Kumar Solingapuram Sai, Anirudh Sattiraju, Frankis G Almaguel, Ang Xuan, Stephanie Rideout, Rahul S Krishnaswamy, JoAnn Zhang, Denise M Herpai, Waldemar Debinski, Akiva Mintz

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. IL13Rα2-Targeting Antibodies for Immuno-PET in Solid Malignancies.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. [Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Annals of nuclear medicine · 2022
    Article
  14. [Redox biology · 2022
    Article
  15. PET Use in Cancer Diagnosis, Treatment, and Prognosis.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Effect of ethanol and cocaine on [Molecular biology reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kiran Kumar Solingapuram Sai *Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Anirudh Sattiraju *Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Frankis G AlmaguelDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Ang XuanDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Stephanie RideoutDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Rahul S KrishnaswamyDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
JoAnn ZhangMicroPET/CT Imaging Section, TriFoil Imaging, Chatsworth, CA, USA.
Denise M HerpaiDepartment of Cancer Biology, Brain Tumor Center of Excellence, Wake Forest School of Medicine, Winston Salem, NC, USA.
Waldemar DebinskiDepartment of Cancer Biology, Brain Tumor Center of Excellence, Wake Forest School of Medicine, Winston Salem, NC, USA.
Akiva MintzDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Wake Forest University · USTriFoil Imaging (United States) · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
TUMOR SPECIFIC TARGET FOR THERAPEUTIC DELIVERIESR01CA074145 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DEBINSKI, WALDEMAR · 1998 to 2019
$4.9M
MR Guided Focused Ultrasound Controlled Stem Cell Therapy for Brain TumorR01CA184091 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI LI, KING C. · 2014 to 2018
$1.6M
Therapeutically Exploiting a Newly Isolated Neural-Like Stem Cell Against GSBR01CA179072 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MINTZ, AKIVA · 2015 to 2020
$1.6M
NCATS NIH HHS UL1 TR001420NCI NIH HHS P30 CA012197NCI NIH HHS R01 CA074145NCI NIH HHS R01 CA179072NCI NIH HHS R01 CA184091
6 · The paper itself

Abstract

Peptides that target cancer cell surface receptors are promising platforms to deliver diagnostic and therapeutic payloads specifically to cancer but not normal tissue. IL13RA2 is a tumor-restricted receptor found to be present in several aggressive malignancies, including in the vast majority of high-grade gliomas and malignant melanoma. This receptor has been successfully targeted for diagnostic and therapeutic purposes using modified IL-13 ligand and more recently using a specific peptide, Pep-1L. In the current work, we establish the

Indexed as

biodistributiondoxycyclinehigh-grade gliomaIL13RA2positron emission tomography (PET)

Identifiers

PMID28881623
PMCPMC5584224
OpenAlexW2599738999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.