Evidence map›Paper›PMID 28880698›Full record

Trial reportJournal of medical economics2018

Cost-effectiveness of a chronic pain intervention for people living with HIV (PLWH).

Jessica S Merlin, Andrew O Westfall, Mallory O Johnson, Robert D Kerns, Matthew J Bair, Stefan Kertesz, Janet M Turan, Olivio J Clay, Joanna L Starrels, Meredith Kilgore

2 registry-linked trialsOpen access · greenAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of medical economics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02824562 nacompletednot on this map

Development of a Behavioral Intervention for Chronic Pain in Individuals With HIV

TypeinterventionalSponsorUniversity of PittsburghRan2016 to 2017Enrolled44ConditionsChronic PainArmsIntervention, Control
NCT03692611 nacompletednot on this mapstarted 2019, after this paper: background citation

Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV

TypeinterventionalSponsorUniversity of PittsburghRan2019 to 2025Enrolled278ConditionsChronic PainArmsSkills TO Manage Pain (STOMP), Comparison group
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jessica S Merlina Division of Infectious Diseases , University of Alabama at Birmingham , Birmingham , AL , USA.
Andrew O Westfalla Division of Infectious Diseases , University of Alabama at Birmingham , Birmingham , AL , USA.
Mallory O Johnsond Department of Medicine , University of California-San Francisco , San Francisco , CA , USA.
Robert D Kernse Pain Research, Informatics, Multimorbidities and Education (PRIME) Center, VA Connecticut Healthcare System , West Haven , CT , USA.
Matthew J Bairg Veterans Affairs Health Services Research & Development Center for Health Information and Communication , Indianapolis , IN , USA.
Stefan Kerteszj Birmingham VA Medical Center , Birmingham , AL , USA.
Janet M Turanl Department of Health Care Organization and Policy, School of Public Health , University of Alabama at Birmingham , Birmingham , AL , USA.
Olivio J Claym Department of Psychology, College of Arts and Sciences , University of Alabama at Birmingham , Birmingham , AL , USA.
Joanna L Starrelsn Albert Einstein College of Medicine and Montefiore Medical Center , Bronx , NY , USA.
Meredith Kilgorel Department of Health Care Organization and Policy, School of Public Health , University of Alabama at Birmingham , Birmingham , AL , USA.
University of Alabama at Birmingham · USAlbert Einstein College of Medicine · USRegenstrief Institute · USUniversity of California, San Francisco · USYale University · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
Prescription opioid use, misuse, disorders and HIV outcomesR01DA039046 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STARRELS, JOANNA L. · 2015 to 2018
$2.4M
Mentoring and Empowerment in the Context of HIV Care for At-Risk PopulationsK24DA037034 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2014 to 2018
$918k
Development of a Behavioral Intervention for Chronic Pain in Individuals with HIVK23MH104073 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERLIN, JESSICA S · 2015 to 2018
$732k
NIAID NIH HHS P30 AI027763NIDA NIH HHS K24 DA037034NIDA NIH HHS R01 DA039046NIMH NIH HHS K23 MH104073
6 · The paper itself

Abstract

backgroundChronic pain is a common, disabling, and costly comorbidity, particularly in people living with HIV (PLWH). This study developed and pilot tested a pain self-management intervention for chronic pain tailored to PLWH called Skills TO Manage Pain (STOMP).

objectivesGiven the additional resources needed to deliver STOMP in HIV clinical settings, an important objective of the pilot study was to assess not only STOMP's preliminary efficacy, but also its cost-effectiveness. RESEARCH DESIGN AND SUBJECTS: The present study draws from a 44-participant, 2-arm randomized pilot trial of the STOMP intervention vs usual care among PLWH and at least moderate chronic pain (Clinicaltrials.gov: NCT02824562). Cost-effectiveness is presented as the incremental cost-effectiveness ratio (ICER). Costs were considered from the clinic perspective over a 1-year time horizon using real costs from the pilot trial. It was conservatively assumed there would be no costs savings. The Standard Gamble (SG) method was used to directly measure utilities.

resultsThirty-six participants met inclusion criteria for the present analyses. Mean age was 52 years; 61% were female and 86% were black. The total cost of STOMP was $483.83 per person. Using the SG method, the change in QALYs was 0.15, corresponding to an ICER of $3,225.

conclusionsSTOMP's cost/QALY is substantially lower than the $50,000 to $100,000/QALY benchmark often used to indicate cost-effectiveness. Although based on a pilot trial and, therefore, preliminary, these findings are promising, and suggest the importance of cost analyses in future STOMP trials.

Indexed as

Cost-Benefit AnalysisAgedAnalysis of VarianceAntiviral AgentsChronic PainComorbidityDouble-Blind MethodFemaleHIV InfectionsHumansMaleMiddle AgedMonte Carlo MethodPain ManagementPilot ProjectsQuality-Adjusted Life YearsAntiviral Agentscost-effectivenessHIVpainSelf-managementutilities

Identifiers

PMID28880698
PMCPMC6028014
OpenAlexW2752846696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.