Evidence map›Paper›PMID 28880230›Full record

ArticleMolecules (Basel, Switzerland)2017

Design, Synthesis, Antimycobacterial Evaluation, and In Silico Studies of 3-(Phenylcarbamoyl)-pyrazine-2-carboxylic Acids.

Lucia Semelková, Petra Janošcová, Carlos Fernandes, Ghada Bouz, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Lucie Navrátilová, Jiří Kuneš, Martin Doležal and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  4. Synthesis, Biological Evaluation, and In Silico Modeling ofPharmaceuticals (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Lucia SemelkováFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. semelkol@faf.cuni.cz.
Petra JanošcováFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. Petra.Janoscova@seznam.cz.
Carlos FernandesFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. oaksdonsad@gmail.com.
Ghada BouzFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. bouzg@faf.cuni.cz.
Ondřej JanďourekFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. JANDO6AA@faf.cuni.cz.
Klára KonečnáFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. konecna@faf.cuni.cz.
Pavla PaterováDepartment of Clinical Microbiology, University Hospital, Sokolská 581, Hradec Králové 500 05, Czech Republic. pavla.paterova@fnhk.cz.
Lucie NavrátilováFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. navratl2@faf.cuni.cz.
Jiří KunešFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. kunes@faf.cuni.cz.
Martin DoležalFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. dolezalm@faf.cuni.cz.ORCID 0000-0003-1558-6625
Jan ZitkoFaculty of Pharmacy in Hradec Králové, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czech Republic. jan.zitko@faf.cuni.cz.
Charles University · CZUniversity Hospital Hradec Králové · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrazinamide, the first-line antitubercular drug, has been regarded the basic component of tuberculosis treatment for over sixty years. Researchers have investigated its effect on

Indexed as

Alcohol OxidoreductasesAnti-Bacterial AgentsAntifungal AgentsBacterial ProteinsComputer SimulationDrug DesignHumansMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureMycobacterium tuberculosisPyrazinesStructure-Activity RelationshipAlcohol OxidoreductasesAnti-Bacterial AgentsAntifungal AgentsBacterial ProteinsDprE1 protein, Mycobacterium tuberculosisPyrazinesanilidesantimycobacterial activitycytotoxicityDprE1pyrazinamidepyrazinoic acidRpsA

Identifiers

PMID28880230
PMCPMC6151461
OpenAlexW2752694743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.