Evidence map›Paper›PMID 28880116›Full record

ArticleJournal of dental research2018

Photoacoustic Imaging for Noninvasive Periodontal Probing Depth Measurements.

C Y Lin, F Chen, A Hariri, C J Chen, P Wilder-Smith, T Takesh, J V Jokerst

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Photoacoustic Imaging for Periodontal Disease Examination.Journal of lasers in medical sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C Y Lin1 Department of NanoEngineering, University of California, San Diego, La Jolla, CA, USA.
F Chen1 Department of NanoEngineering, University of California, San Diego, La Jolla, CA, USA.
A Hariri1 Department of NanoEngineering, University of California, San Diego, La Jolla, CA, USA.
C J Chen1 Department of NanoEngineering, University of California, San Diego, La Jolla, CA, USA.
P Wilder-Smith3 Beckman Laser Institute, University of California, Irvine, CA, USA.
T Takesh3 Beckman Laser Institute, University of California, Irvine, CA, USA.
J V Jokerst1 Department of NanoEngineering, University of California, San Diego, La Jolla, CA, USA.

Funding

Therapeutic Drug Monitoring with a Wearable Ultrasound-based SensorDP2HL137187 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2016 to 2019
$2.7M
A Therapeutic Tool for Ultrasound-Guided Stem Cell TherapyR00HL117048 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2015 to 2017
$747k
Vevo LAZR Photoacoustic Imaging SystemS10OD021821 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALL, DAVID J · 2016 to 2016
$594k
NHLBI NIH HHS DP2 HL137187NHLBI NIH HHS R00 HL117048NIH HHS S10 OD021821
6 · The paper itself

Abstract

The periodontal probe is the gold standard tool for periodontal examinations, including probing depth measurements, but is limited by systematic and random errors. Here, we used photoacoustic ultrasound for high-spatial resolution imaging of probing depths. Specific contrast from dental pockets was achieved with food-grade cuttlefish ink as a contrast medium. Here, 39 porcine teeth (12 teeth with artificially deeper pockets) were treated with the contrast agent, and the probing depths were measured with novel photoacoustic imaging and a Williams periodontal probe. There were statistically significant differences between the 2 measurement approaches for distal, lingual, and buccal sites but not mesial. Bland-Altman analysis revealed that all bias values were < ±0.25 mm, and the coefficients of variation for 5 replicates were <11%. The photoacoustic imaging approach also offered 0.01-mm precision and could cover the entire pocket, as opposed to the probe-based approach, which is limited to only a few sites. This report is the first to use photoacoustic imaging for probing depth measurements with potential implications to the dental field, including tools for automated dental examinations or noninvasive examinations.

Indexed as

AnimalsContrast MediaGingivaMicroscopy, Electron, TransmissionPeriodontal PocketPeriodontiumPhotoacoustic TechniquesSwineUltrasonographyContrast Mediadental contrast agentgingival thicknessmelanin nanoparticlesperiodontal exampocket depthultrasound imaging

Identifiers

PMID28880116
PMCPMC5755810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.