ArticleMaterials (Basel, Switzerland)2011
A New Highly Bioactive Composite for Scaffold Applications: A Feasibility Study.
Article in Materials (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 38 citations in OpenAlex.
- PMMA bone cement with L-arginine/nano fish bone nanocomplex for apatite formation.Royal Society open science · 2024Article
- Comparison of Three Manufacturing Techniques for Sustainable Porous Clay Ceramics.Materials (Basel, Switzerland) · 2020Article
- A Novel Bioactive Glass Containing Therapeutic Ions with Enhanced Biocompatibility.Materials (Basel, Switzerland) · 2020Article
- Novel antimicrobial phosphate-free glass-ceramic scaffolds for bone tissue regeneration.Scientific reports · 2020Article
- Advanced Open-Celled Structures from Low-Temperature Sintering of a Crystallization-Resistant Bioactive Glass.Materials (Basel, Switzerland) · 2019Article
- Microstructure Evolution and Mechanical Properties Improvement in Liquid-Phase-Sintered Hydroxyapatite by Laser Sintering.Materials (Basel, Switzerland) · 2015Article
- Characterization and Stability of Tanshinone IIA Solid Dispersions with Hydroxyapatite.Materials (Basel, Switzerland) · 2013Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
Hydroxyapatite (HA) has been widely investigated as scaffolding material for bone tissue engineering, mainly for its excellent biocompatibility. Presently, there is an increasing interest in the composites of hydroxyapatite with bioactive glasses, with the aim to obtain systems with improved bioactivity or mechanical properties. Moreover, modifying the ratio between bioactive glass and hydroxyapatite results in the possibility of controlling the reaction rate of the composite scaffold in the human body. However, high temperature treatments are usually required in order to sinter HA-based composites, causing the bioactive glass to crystallize into a glass-ceramic, with possible negative effects on its bioactivity. In the present research work, a glass composition belonging to the Na₂O-CaO-P₂O₅-SiO₂ system, with a reduced tendency to crystallize, is applied to realize HA-based composites. The novel samples can be sintered at a relative low temperature (750 °C) compared to the widely studied HA/45S5 Bioglass
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