Evidence map›Paper›PMID 28879956›Full record

ArticleMaterials (Basel, Switzerland)2011

Role of Titanium Surface Topography and Surface Wettability on Focal Adhesion Kinase Mediated Signaling in Fibroblasts.

Christine J Oates, Weiyan Wen, Douglas W Hamilton

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Ceramic 3D-Printed Titanium Cranioplasty.Craniomaxillofacial trauma & reconstruction · 2020
    Article
  8. Article
  9. Enhanced Human Gingival Fibroblast Response and ReducedBioMed research international · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Isolation of primary osteoblast cell lines from adult rat and rat embryos and their use as models for in vitro biocompatibility tests of nanostructured titanium-based implants.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2017
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christine J OatesGraduate Program of Biomedical Engineering, The University of Western Ontario, London, N6A 5B9 Ontario, Canada. coates@uwo.ca.
Weiyan WenDivision of Oral Biology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario N6A 5C1, Canada. wwen@uwo.ca.
Douglas W HamiltonGraduate Program of Biomedical Engineering, The University of Western Ontario, London, N6A 5B9 Ontario, Canada. dhamil2@uwo.ca.
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes of titanium surface roughness and surface free energy may influence protein absorption that increases cell differentiation through activation of focal adhesion kinase related pathways. However, the influence of titanium surface roughness and hydrophilicity on fibroblast behavior is not well understood. The aim of this study was to investigate the influence of topography and hydrophilicity on fibroblast attachment, spreading, morphology, intracellular signaling, proliferation, and collagen I mRNA levels. Using a cellular FAK knockout (FAK

Indexed as

adhesive signalingfibroblastfocal adhesion kinasesubstratum roughnesstissue regenerationtitaniumwettability

Identifiers

PMID28879956
PMCPMC5448591
OpenAlexW2170800504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.