Evidence map›Paper›PMID 28879632›Full record

ArticleBrain topography2018

Real-Time Clustered Multiple Signal Classification (RTC-MUSIC).

Christoph Dinh, Lorenz Esch, Johannes Rühle, Steffen Bollmann, Daniel Güllmar, Daniel Baumgarten, Matti S Hämäläinen, Jens Haueisen

Abstract read
In one paragraph

Article in Brain topography, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christoph DinhAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital - Massachusetts Institute of Technology - Harvard Medical School, 149 13th St., Charlestown, MA, 02129, USA. chdinh@nmr.mgh.harvard.edu.ORCID 0000-0002-0313-0228
Lorenz EschInstitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany.
Johannes RühleInstitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany.
Steffen BollmannInstitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany.
Daniel GüllmarMedical Physics Group, Institute of Diagnostic and Interventional Radiology, University Hospital Jena, Jena, Germany.
Daniel BaumgartenInstitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany.
Matti S HämäläinenAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital - Massachusetts Institute of Technology - Harvard Medical School, 149 13th St., Charlestown, MA, 02129, USA.
Jens HaueisenInstitute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany.

Funding

Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
Device-Independent Acquisition and Real Time Spatiotemporal Analysis of Clinical Electrophysiology DataU01EB023820 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI MOSHER, JOHN COMPTON, OKADA, YOSHIO · 2017 to 2021
$5.8M
Tools for Large-Scale Platform-Independent MEG Data AnalysisR01EB009048 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI HAMALAINEN, MATTI, LEAHY, RICHARD M · 2009 to 2016
$4.6M
Deutsche Forschungsgemeinschaft Ba 4858/1-1Horizon 2020 686865NIBIB NIH HHS P41 EB015896NIBIB NIH HHS R01 EB009048NIBIB NIH HHS U01 EB023820NIH HHS 4R01EB009048NIH HHS 5P41EB015896Thüringer Ministerium für Bildung, Wissenschaft und Kultur 2015 FGR 0085
6 · The paper itself

Abstract

Magnetoencephalography (MEG) and electroencephalography provide a high temporal resolution, which allows estimation of the detailed time courses of neuronal activity. However, in real-time analysis of these data two major challenges must be handled: the low signal-to-noise ratio (SNR) and the limited time available for computations. In this work, we present real-time clustered multiple signal classification (RTC-MUSIC) a real-time source localization algorithm, which can handle low SNRs and can reduce the computational effort. It provides correlation information together with sparse source estimation results, which can, e.g., be used to identify evoked responses with high sensitivity. RTC-MUSIC clusters the forward solution based on an anatomical brain atlas and optimizes the scanning process inherent to MUSIC approaches. We evaluated RTC-MUSIC by analyzing MEG auditory and somatosensory data. The results demonstrate that the proposed method localizes sources reliably. For the auditory experiment the most dominant correlated source pair was located bilaterally in the superior temporal gyri. The highest activation in the somatosensory experiment was found in the contra-lateral primary somatosensory cortex.

Indexed as

AlgorithmsAtlases as TopicBrainBrain MappingCluster AnalysisElectroencephalographyEvoked Potentials, AuditoryEvoked Potentials, SomatosensoryFunctional LateralityHumansMagnetoencephalographySignal-To-Noise RatioK-means clusteringPowell’s conjugate direction methodRAP-MUSICReal-timeRTC-MUSICSource estimation

Identifiers

PMID28879632
PMCPMC5773364

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.