ArticleOral and maxillofacial surgery2017
The risk factors associated with postoperative hemorrhage after tooth extraction: a multi-center retrospective study of patients receiving oral antithrombotic therapy.
Article in Oral and maxillofacial surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Dental Complications in Antithrombotic Patients: Evidence From a Nationwide Cohort and a Single-Institution Dataset.International dental journal · 2026Article
- Maxillary Tuberosity Fractures: A Structured Narrative Review and Clinical Decision-Making Considerations.Healthcare (Basel, Switzerland) · 2026Review
- Classification of postoperative bleeding severity by general dental practitioners in the National Dental Practice-Based Research Network: a survey-based assessment.Quintessence international (Berlin, Germany : 1985) · 2025Article
- Severe Hemorrhage Following Dental Implant Surgery in an Anticoagulated Elderly Patient: A Case Report.Cureus · 2025Article
- Risk of post-operative bleeding after dentoalveolar surgery in patients taking anticoagulants: a cohort study using the common data model.Scientific reports · 2024Article
- Experts' consensus on perioperative management of tooth extractions in patients receiving oral antithrombotic treatment.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- Risk factors for bleeding after dental extractions in patients receiving antithrombotic drugs - A case control study.Journal of dental sciences · 2022Article
- The incidence of postoperative hemorrhage after tooth extraction in patients with thrombocytopenia.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2021Article
- Comparison of cardiovascular response between patients on warfarin and hypertensive patients not on warfarin during dental extraction.Clinical oral investigations · 2021Article
- Is telephone follow-up useful in preventing post-extraction bleeding in patients on antithrombotic treatment?Journal of clinical and experimental dentistry · 2021Article
- Article
- Salivary tissue factor induces thrombin generation in a diurnal rhythm.Research and practice in thrombosis and haemostasis · 2018Article
- Bleeding Complications in Relation to the International Normalized Ratio for Dental Extractions in Patients under Chronic Anticoagulant Therapy - An Evaluative Study.Annals of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to retrospectively investigate the multivariate relationships between specific risk factors and postoperative hemorrhage after tooth extraction in patients who were prescribed oral antithrombotic therapy. Risk factors for postoperative hemorrhage after tooth extraction were evaluated using univariate and multivariate analyses. Patient characteristics such as age and gender; the presence or absence of known comorbidities such as diabetes mellitus, hypertension, cerebral infarction, and alcohol consumption; and perioperative diarrhea were assessed. The drug used for antithrombotic therapy, preoperative blood test results, the presence or absence of preoperative antibiotics or nonsteroidal anti-inflammatory drug (NSAID) administration, the total number of extracted teeth, and the type of surgical procedures were also evaluated. We found that the preoperative administration of antibiotics (odds ratio (OR) = 2.52), an increased prothrombin time international normalized ratio (PT-INR) value (OR = 1.94), and the extraction of multiple teeth (OR = 2.10) were significantly associated with postoperative hemorrhage. There was no significant association between postoperative hemorrhage and any other demographic factors or comorbidities, including concomitant alcohol use. We demonstrated the multivariate relationship between the risk factors and postoperative hemorrhage after tooth extraction in patients receiving oral antithrombotic therapy. Surgeons should be aware of these risks and monitor the PT-INR of anticoagulated patients.
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