ArticleDigestive diseases and sciences2017
Comparison of ICD-9 Codes for Depression and Alcohol Misuse to Survey Instruments Suggests These Codes Should Be Used with Caution.
Article in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 22 citations in OpenAlex.
- Hearing Loss Is Associated With Depression and Dysthymia in the All of Us Research Program.The Laryngoscope · 2025Article
- One Third of Alcohol Use Disorder Diagnoses are Missed by ICD Coding.Substance use & addiction journal · 2025Article
- The Association Between Hearing Loss and Depression in a Large Electronic Health Record System.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Alcohol Withdrawal Severity Measures for Identifying Patients Requiring High-Intensity Care.Critical care explorations · 2024Article
- Influence of depression on breast cancer treatment and survival: A Kentucky population-based study.Cancer · 2023Article
- The Association of Antenatal Depression and Cesarean Delivery among First-Time Parturients: A Population-Based Study.American journal of perinatology · 2023Article
- Article
- Antenatal Depression and Cesarean Delivery Among Recently-Delivered Nulliparous Women in Rhode Island.Rhode Island medical journal (2013) · 2022Article
- Characterizing the Variation of Alcohol Cessation Pharmacotherapy in Primary Care.Journal of general internal medicine · 2021Article
- Linkage to specialty care in the hepatitis C care cascade.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021Article
- Mental health status in veterans residing in rural versus non-rural areas: results from the veterans' health study.Military Medical Research · 2020Article
- Publicly available machine learning models for identifying opioid misuse from the clinical notes of hospitalized patients.BMC medical informatics and decision making · 2020Observational
- Article
- Geographical Disparities of Outcomes of Hepatocellular Carcinoma in France: The Heavier Burden of Alcohol Compared to Hepatitis C.Digestive diseases and sciences · 2020Article
- Trends in Psychiatric Hospitalization of Children and Adolescents in Spain between 2005 and 2015.Journal of clinical medicine · 2019Article
- Direct-Acting Antivirals for Hepatitis C: Predictors of Early Discontinuation in the Real World.Journal of managed care & specialty pharmacy · 2019Article
- Mortality Among Patients With Chronic Hepatitis B Infection: The Chronic Hepatitis Cohort Study (CHeCS).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Natural language processing and machine learning to identify alcohol misuse from the electronic health record in trauma patients: development and internal validation.Journal of the American Medical Informatics Association : JAMIA · 2019Observational
- Sofosbuvir-Based Regimens for Chronic Hepatitis C in a Well-Insured U.S. Population: Patient Characteristics, Treatment Adherence, Effectiveness, and Health Care Costs, 2013-2015.Journal of managed care & specialty pharmacy · 2019Article
- Long-Term Liver Disease, Treatment, and Mortality Outcomes Among 17,000 Persons Diagnosed with Chronic Hepatitis C Virus Infection: Current Chronic Hepatitis Cohort Study Status and Review of Findings.Infectious disease clinics of North America · 2018Review
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundResearch suggests depression and alcohol misuse are highly prevalent among chronic hepatitis C (CHC) patients, which is of clinical concern.
aimsTo compare ICD-9 codes for depression and alcohol misuse to validated survey instruments.
methodsAmong CHC patients, we assessed how well electronic ICD-9 codes for depression and alcohol misuse predicted these disorders using validated instruments.
resultsOf 4874 patients surveyed, 56% were male and 52% had a history of injection drug use. Based on the PHQ-8, the prevalence of depression was 30% compared to 14% based on ICD-9 codes within 12 months of survey, 37% from ICD-9 codes any time before or within 12 months after survey, and 48% from ICD-9 codes any time before or within 24 months after survey. ICD-9 codes predicting PHQ-8 depression had a sensitivity ranging from 59 to 88% and a specificity ranging from 33 to 65%. Based on the AUDIT-C, the prevalence of alcohol misuse was 21% compared to 3-23% using ICD-9 codes. The sensitivity of ICD-9 codes to predict AUDIT-C score ranged from 9 to 35% and specificity from 80 to 98%. Overall 39% of patients reported ever binge drinking, with a sensitivity of ICD-9 to predict binge drinking ranging from 7 to 33% and a specificity from 84 to 98%. More than half of patients had either an ICD-9 code for depression, a survey score indicating depression, or both (59%); more than one-third had the same patterns for alcohol misuse (36%).
conclusionsICD-9 codes were limited in predicting current depression and alcohol misuse, suggesting that caution should be exercised when using ICD-9 codes to assess depression or alcohol misuse among CHC patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.