ArticleJournal of autism and developmental disorders2017
Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development.
Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Relationship Between Intellectual Disability and Behavioral Comorbidity in Children With Fragile X Syndrome.Journal of autism and developmental disorders · 2025Article
- A framework for parsing psychopathological heterogeneity: initial application in a large-scale unselected community sample.BMC psychiatry · 2025Article
- Latent Class Analysis Identifies Distinctive Behavioral Subtypes in Children with Fragile X Syndrome.Journal of autism and developmental disorders · 2024Article
- Identification of subgroups of children in the Australian Autism Biobank using latent class analysis.Child and adolescent psychiatry and mental health · 2023Article
- Examining Phenotypical Heterogeneity in Language Abilities in Chinese-Speaking Children with Autism: A Naturalistic Sampling Approach.Journal of autism and developmental disorders · 2022Article
- Features that best define the heterogeneity and homogeneity of autism in preschool-age children: A multisite case-control analysis replicated across two independent samples.Autism research : official journal of the International Society for Autism Research · 2022Article
- Identifying Subgroups of Toddlers with DSM-5 Autism Spectrum Disorder Based on Core Symptoms.Journal of autism and developmental disorders · 2021Article
- Article
- Mapping the Relationship between Dysmorphology and Cognitive, Behavioral, and Developmental Outcomes in Children with Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2020Article
- Approaches to Defining Common and Dissociable Neurobiological Deficits Associated With Psychopathology in Youth.Biological psychiatry · 2020Review
- Article
- The Physical and Mental Health of Middle Aged and Older Adults on the Autism Spectrum and the Impact of Intellectual Disability.Research in autism spectrum disorders · 2019Article
- The Heterogeneity Problem: Approaches to Identify Psychiatric Subtypes.Trends in cognitive sciences · 2019Review
- A Phenotype of Childhood Autism Is Associated with Preexisting Maternal Anxiety and Depression.Journal of abnormal child psychology · 2019Article
- Associations between parental broader autism phenotype and child autism spectrum disorder phenotype in the Study to Explore Early Development.Autism : the international journal of research and practice · 2019Article
- A matter of time: The necessity of temporal language in research on health conditions that present with autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2019Review
- Reading outcomes in children with developmental language disorder: A person-centered approach.Autism & developmental language impairmentsArticle
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Authors and funding
13 authors.
Funding
Abstract
The objective of this study was to identify homogenous classes of young children with autism spectrum disorder (ASD) to improve phenotypic characterization. Children were enrolled in the Study to Explore Early Development between 2 and 5 years of age. 707 children were classified with ASD after a comprehensive evaluation with strict diagnostic algorithms. Four classes of children with ASD were identified from latent class analysis: mild language delay with cognitive rigidity, mild language and motor delay with dysregulation, general developmental delay, and significant developmental delay with repetitive motor behaviors. We conclude that a four-class phenotypic model of children with ASD best describes our data and improves phenotypic characterization of young children with ASD. Implications for screening, diagnosis, and research are discussed.
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Registered trials
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