Evidence map›Paper›PMID 28879231›Full record

ArticleScience advances2017

Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in

Katy Hedgethorne, Sebastian Eustermann, Ji-Chun Yang, Tom E H Ogden, David Neuhaus, Gareth Bloomfield

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The molecular foundations of zygosis.Cellular and molecular life sciences : CMLS · 2020
    Review
  6. Triparental inheritance inProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Katy HedgethorneMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Sebastian EustermannMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Ji-Chun YangMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Tom E H OgdenMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
David NeuhausMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Gareth BloomfieldMRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
MRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_U105115237Medical Research Council MC_U105178934Medical Research Council MC_U105184330Medical Research Council U105178934
6 · The paper itself

Abstract

Homeodomain proteins control the developmental transition between the haploid and diploid phases in several eukaryotic lineages, but it is not known whether this regulatory mechanism reflects the ancestral condition or, instead, convergent evolution. We have characterized the mating-type locus of the amoebozoan

Indexed as

DiploidyHaploidyAmino Acid SequenceConserved SequenceDictyosteliumDNA-Binding ProteinsHomeodomain ProteinsLife Cycle StagesMagnetic Resonance SpectroscopyModels, BiologicalModels, MolecularProtein ConformationProtozoan ProteinsStructure-Activity RelationshipDNA-Binding ProteinsHomeodomain ProteinsProtozoan Proteins

Identifiers

PMID28879231
PMCPMC5580921
OpenAlexW2753449956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.