ReviewFrontiers in pediatrics2017
The Genomics of Neonatal Abstinence Syndrome.
Review in Frontiers in pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Neonatal Opioid Withdrawal Syndrome: 2 Years Later…Where Are We NOWS?The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Trends of prenatal opioid utilization and neonatal abstinence syndrome in Manitoba, Canada: A 26-year population-based cohort study.Paediatrics & child health · 2025Article
- The acoustic properties, syllable structure, and syllable sequences of ultrasonic vocalizations (USVs) during neonatal opioid withdrawal in FVB/N mouse substrains.Addiction neuroscience · 2025Article
- Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice.Neuropharmacology · 2023Article
- Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice.bioRxiv : the preprint server for biology · 2023Article
- Sex-specific inflammatory and white matter effects of prenatal opioid exposure: a pilot study.Pediatric research · 2023Article
- Neonatal opioid withdrawal syndrome: a review of the science and a look toward the use of buprenorphine for affected infants.Journal of perinatology : official journal of the California Perinatal Association · 2022Review
- Racial differences in opioid withdrawal syndrome among neonates with intrauterine opioid exposure.Pediatric research · 2021Observational
- Commentary on salivary cortisol levels as a biomarker for severity of withdrawal in opioid-exposed newborns.Pediatric research · 2020Article
- Racial association and pharmacotherapy in neonatal opioid withdrawal syndrome.Journal of perinatology : official journal of the California Perinatal Association · 2019Observational
- Review
- Methadone dosing strategies in preterm neonates can be simplified.British journal of clinical pharmacology · 2019Article
- Sex-Specific Gene Expression in the Mouse Nucleus Accumbens Before and After Cocaine Exposure.Journal of the Endocrine Society · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Significant variability has been observed in the development and severity of neonatal abstinence syndrome (NAS) among neonates exposed to prenatal opioids. Since maternal opioid dose does not appear to correlate directly with neonatal outcome, maternal, placental, and fetal genomic variants may play important roles in NAS. Previous studies in small cohorts have demonstrated associations of variants in maternal and infant genes that encode the μ-opioid receptor (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.