Evidence map›Paper›PMID 28879085›Full record

ArticleNeuroImage. Clinical2017

Progressive medial temporal lobe atrophy during preclinical Alzheimer's disease.

Corinne Pettigrew, Anja Soldan, Kelly Sloane, Qing Cai, Jiangxia Wang, Mei-Cheng Wang, Abhay Moghekar, Michael I Miller, Marilyn Albert, BIOCARD Research Team

Open access · goldAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

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  7. Clinical significance of the cognition-related pathogenic proteins in plasma neuronal-derived exosomes among normal cognitive adults over 45 years old with olfactory dysfunction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Corinne PettigrewDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, United States.
Anja SoldanDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, United States.
Kelly SloaneDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, United States.
Qing CaiDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Jiangxia WangDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Mei-Cheng WangDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Abhay MoghekarDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, United States.
Michael I MillerDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, United States.
Marilyn AlbertDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, United States.
BIOCARD Research Team
Johns Hopkins University · US

Funding

Project 2 MeasurementU19AG033655 · NIA · JOHNS HOPKINS UNIVERSITY · PI JUAN TRONCOSO · 2014 to 2026
$51.5M
'T V ASSESSMENT - MEMORY DISORDERED PATIENTS'P50AG005146 · NIA · JOHNS HOPKINS UNIVERSITY · PI TRONCOSO, JUAN · 1985 to 2019
$37.6M
TR&D 4: Algorithms for functional and anatomical brain analysisP41EB015909 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MORI, SUSUMU · 2012 to 2020
$13.1M
NIA NIH HHS P50 AG005146NIA NIH HHS U19 AG033655NIBIB NIH HHS P41 EB015909
6 · The paper itself

Abstract

This study examined whether longitudinal MRI trajectories in medial temporal lobe (MTL) brain regions differed among groups of cognitively normal individuals defined by their cerebrospinal fluid (CSF) levels when they were first enrolled (

Indexed as

Disease ProgressionProdromal SymptomsAgedAlzheimer DiseaseAmyloid beta-PeptidesAtrophyCognitive DysfunctionFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingMaleMiddle Agedtau ProteinsTemporal LobeAmyloid beta-Peptidestau ProteinsAmyloidCerebrospinal fluidMagnetic resonance imagingPhosphorylated tauPreclinical AD

Identifiers

PMID28879085
PMCPMC5577409
OpenAlexW2745853351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.