ArticleBMJ open diabetes research & care2017
Medication adherence and glycemic control among newly diagnosed diabetes patients.
Article in BMJ open diabetes research & care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.
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Who cites it
65 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- What is the effect of mobile phone text message reminders on medication adherence among adult type 2 diabetes mellitus patients: a systematic review and meta-analysis of randomized controlled trials.BMC endocrine disorders · 2023Pooled it
- Understanding the influence of ethnicity on adherence to antidiabetic medication: Meta-ethnography and systematic review.PloS one · 2023Pooled it
- Pooled it
- A Smartphone App to Improve Medication Adherence in Patients With Type 2 Diabetes in Asia: Feasibility Randomized Controlled Trial.JMIR mHealth and uHealth · 2019Trial
- Development and Validation of a Machine Learning Model for Predicting Medication Adherence Among Home-Dwelling Elderly Patients: A Retrospective Cross-Sectional Study.Patient preference and adherence · 2026Article
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- Article
- Unmasking the Emotional and Behavioral Determinants of Glycemic Control in Diabetes Management.Cureus · 2025Article
- Mediating role of disease acceptance in the relationship between social support and adherence to treatment in patients with type 2 diabetes.Journal of behavioral medicine · 2025Article
- Beyond Glycaemia: Socioeconomic Factors and Diabetes Distress are Associated with Health-Related Quality of Life in People with Type 2 Diabetes.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- Dual effects ofNarra J · 2025Article
- Article
- Fifteen-year trends in diabetes drug management and control in French-speaking Switzerland.Diabetology & metabolic syndrome · 2025Article
- Association of the glycemic background patterns and the diabetes management efficacy in poorly controlled type 2 diabetes.World journal of diabetes · 2025Article
- Understanding the struggle: Unique challenges of adherence in male diabetic patients in Tshwane.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024Article
- Review on the Role of Polyphenols in Preventing and Treating Type 2 Diabetes: Evidence from In Vitro and In Vivo Studies.Nutrients · 2024Review
- The Impact of Medication Regimen Adjustment Ratio on Adherence and Glycemic Control in Patients with Type 2 Diabetes and Mild Cognitive Impairment.Biomedicines · 2024Article
- Effect of Food Consumption on the Pharmacokinetics, Safety, and Tolerability of Once-Daily Orally Administered Orforglipron (LY3502970), a Non-peptide GLP-1 Receptor Agonist.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024Article
- Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data.BMC medicine · 2024Article
- Diabetes and chronic kidney disease in Chinese adults: a population-based cohort study.BMJ open diabetes research & care · 2024Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPoor medication adherence can have negative consequences for the patients, the provider, the physician, and the sustainability of the healthcare system. To our knowledge, the association between medication adherence and glycemic control among newly diagnosed diabetes patients has not been studied. This study aims to bridge the gap.
methodThis is a retrospective cohort study of 2463 patients managed in the National Healthcare Group in Singapore with newly diagnosed diabetes. Patients were followed up for the first two years from their first medication dispensed for measuring medication adherence, proportion of days covered (PDC); and for another three years for investigating outcomes of glycemic control, emergency department visit, and hospitalization. Multivariable regressions were performed to study the association between medication adherence and the outcomes as well as the risk factors of poor adherence.
resultsThe prevalence of medication adherence (PDC≥80%) was 65.0% (95% CI 63.1% to 66.9%) among newly diagnosed diabetes patients in Singapore. Male, Indian, or patients without hypertension or dyslipidemia were associated with poorer medication adherence. The HbA1c level of poor adherent patients (PDC <40%) increased by 0.4 (95% CI 0.2 to 0.5) over the two years, and they were also more likely to have hospitalization (OR 2.6,95% CI 1.7 to 3.8) or emergency department visit (OR 2.4,95% CI 1.7 to 3.4) compared with the fully adherent patients (PDC=100%).
conclusionsThe medication adherence in the early stage of diabetes is important for maximizing the effectiveness of pharmaceutical therapy. Health policies or interventions targeting the improvement of medication adherence among newly diagnosed diabetes patients are in need.
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