Evidence map›Paper›PMID 28878894›Full record

ArticleJournal of animal science and biotechnology2017

Genomic regions and pathways associated with gastrointestinal parasites resistance in Santa Inês breed adapted to tropical climate.

Mariana Piatto Berton, Rafael Medeiros de Oliveira Silva, Elisa Peripolli, Nedenia Bonvino Stafuzza, Jesús Fernández Martin, Maria Saura Álvarez, Beatriz Villanueva Gavinã, Miguel Angel Toro, Georgget Banchero, Priscila Silva Oliveira and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  12. Genome-Wide Association Study forPathogens (Basel, Switzerland) · 2022
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  18. Copy Number Variants in Four Italian Turkey Breeds.Animals : an open access journal from MDPI · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Mariana Piatto BertonDepartamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Via de acesso Prof. Paulo Donato Castellane, s/no, Jaboticabal, SP CEP 14884-900 Brazil.
Rafael Medeiros de Oliveira SilvaDepartamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Via de acesso Prof. Paulo Donato Castellane, s/no, Jaboticabal, SP CEP 14884-900 Brazil.
Elisa PeripolliDepartamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Via de acesso Prof. Paulo Donato Castellane, s/no, Jaboticabal, SP CEP 14884-900 Brazil.
Nedenia Bonvino StafuzzaDepartamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Via de acesso Prof. Paulo Donato Castellane, s/no, Jaboticabal, SP CEP 14884-900 Brazil.
Jesús Fernández MartinInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, Crta. de la Coruña, km 7,5 -, 28040 Madrid, Spain.
Maria Saura ÁlvarezInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, Crta. de la Coruña, km 7,5 -, 28040 Madrid, Spain.
Beatriz Villanueva GavinãInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA, Crta. de la Coruña, km 7,5 -, 28040 Madrid, Spain.
Miguel Angel ToroDepartamento de Producción Agraria, School of Agricultural, Food and Byosystems Engineering, Universisdad Politécnica de Madrid, Campus Ciudad Universitaria Avda. Complutense 3 - Avda. Puerta Hierro, 28040 Madrid, Spain.
Georgget BancheroInstituto Nacional de Investigación Agropecuária (INIA), Ruta 50 Km. 12, Colonia, Uruguay.
Priscila Silva OliveiraFaculdade de Zootecnia e Engenharia de Alimentos, Nucleo de Apoio à Pesquisa em Melhoramento Animal, Biotecnologia e Transgenia, Universidade de São Paulo, Rua Duque de Caxias Norte, 225, Pirassununga, SP CEP 13635-900 Brazil.
Joanir Pereira ElerFaculdade de Zootecnia e Engenharia de Alimentos, Nucleo de Apoio à Pesquisa em Melhoramento Animal, Biotecnologia e Transgenia, Universidade de São Paulo, Rua Duque de Caxias Norte, 225, Pirassununga, SP CEP 13635-900 Brazil.
Fernando BaldiDepartamento de Zootecnia, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista, Via de acesso Prof. Paulo Donato Castellane, s/no, Jaboticabal, SP CEP 14884-900 Brazil.
José Bento Sterman FerrazFaculdade de Zootecnia e Engenharia de Alimentos, Nucleo de Apoio à Pesquisa em Melhoramento Animal, Biotecnologia e Transgenia, Universidade de São Paulo, Rua Duque de Caxias Norte, 225, Pirassununga, SP CEP 13635-900 Brazil.
Universidade Estadual Paulista (Unesp) · BRInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ESUniversidade de São Paulo · BRInstituto Nacional de Investigación Agropecuaria · UYUniversidad Politécnica de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to estimate variance components and to identify genomic regions and pathways associated with resistance to gastrointestinal parasites, particularly

resultsThe overall linkage disequilibrium (LD) mean between pairs of markers measured by

conclusionThe traits indicating gastrointestinal parasites resistance presented an adequate genetic variability to respond to selection in Santa Inês breed, and it is expected a higher genetic gain for FAM trait when compared to the others. The level of LD estimated for markers separated by less than 1 Mb indicated that the Ovine SNP12k BeadChip might be a suitable tool for identifying genomic regions associated with traits related to gastrointestinal parasite resistance. Several candidate genes related to immune system development and activation, inflammatory response, regulation of lymphocytes and leukocytes proliferation were found. These genes may help in the selection of animals with higher resistance to parasites.

Indexed as

GwasLinkage disequilibriumParasites resistanceSanta Inês breed

Identifiers

PMID28878894
PMCPMC5584554
OpenAlexW2750940243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.