Evidence map›Paper›PMID 28878780›Full record

ArticleFrontiers in immunology2017

P2Y

Tobias Müller, Susanne Fay, Rodolfo Paula Vieira, Harry Karmouty-Quintana, Sanja Cicko, Cemil Korcan Ayata, Gernot Zissel, Torsten Goldmann, Giuseppe Lungarella, Davide Ferrari and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Applications of artificial intelligence in drug discovery for neurological diseases.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  3. Review
  4. Article
  5. CaBiomolecules · 2024
    Review
  6. The microglial P2YTranslational neurodegeneration · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Hyperinflammation and airway surface liquid dehydration in cystic fibrosis: purinergic system as therapeutic target.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
    Review
  12. Purinergic receptors in airway hydration.Biochemical pharmacology · 2021
    Review
  13. Review
  14. Review
  15. Lack of adipocyte purinergic P2YProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Purinergic Dysfunction in Pulmonary Arterial Hypertension.Journal of the American Heart Association · 2020
    Review
  17. P2 Purinergic Signaling in the Distal Lung in Health and Disease.International journal of molecular sciences · 2020
    Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 4 countries.

Tobias MüllerDepartment of Pneumology, University Medical Center Freiburg, Freiburg, Germany.
Susanne FayDepartment of Pneumology, University Medical Center Freiburg, Freiburg, Germany.
Rodolfo Paula VieiraDepartment of Pneumology, University Medical Center Freiburg, Freiburg, Germany.
Harry Karmouty-QuintanaDepartment of Biochemistry and Molecular Biology, University of Texas, Houston, TX, United States.
Sanja CickoDepartment of Pneumology, University Medical Center Freiburg, Freiburg, Germany.
Cemil Korcan AyataDepartment of Pneumology, University Medical Center Freiburg, Freiburg, Germany.
Gernot ZisselDepartment of Pneumology, University Medical Center Freiburg, Freiburg, Germany.
Torsten GoldmannClinical and Experimental Pathology, Research Center Borstel, Borstel, Germany.
Giuseppe LungarellaDepartment of Physiopathology and Experimental Medicine, University of Siena, Siena, Italy.
Davide FerrariDepartment of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Francesco Di VirgilioDepartment of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.
Bernard RobayeIRIBHM and Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Jean-Marie BoeynaemsIRIBHM and Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Eduardo R LazarowskiCystic Fibrosis Research Center, Marsico Lung Institute, University of North Carolina, Chapel Hill, NC, United States.
Michael R BlackburnDepartment of Biochemistry and Molecular Biology, University of Texas, Houston, TX, United States.
Marco IdzkoDepartment of Pneumology, University Medical Center Freiburg, Freiburg, Germany.
University Medical Center Freiburg · DEUniversité Libre de Bruxelles · BEUniversity of Ferrara · ITUniversity of Houston · USResearch Center Borstel - Leibniz Lung Center · DEUniversity of North Carolina at Chapel Hill · USUniversity of Siena · IT

Funding

Purinergic Control of CFTR-ENaC Interactions in Alveolar EpitheliaP01HL110873 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BOUCHER, RICHARD CHARLES · 2012 to 2016
$10.7M
NHLBI NIH HHS P01 HL110873
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and very few available treatment options. The involvement of the purinergic receptor subtypes P2Y

Indexed as

animal modelbleomycininflammationpulmonary fibrosispurinergic receptorsuridine-5′-diphosphate

Identifiers

PMID28878780
PMCPMC5572280
OpenAlexW2746034916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.