Evidence map›Paper›PMID 28878777›Full record

ArticleFrontiers in immunology2017

Zika Virus Promotes Neuronal Cell Death in a Non-Cell Autonomous Manner by Triggering the Release of Neurotoxic Factors.

Isabella G Olmo, Toniana G Carvalho, Vivian V Costa, Juliana Alves-Silva, Carolina Z Ferrari, Tatiane C Izidoro-Toledo, Juliana F da Silva, Antonio L Teixeira, Danielle G Souza, Joao T Marques and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 102 citations in OpenAlex.

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  10. Updating an Overview of Teratology.Methods in molecular biology (Clifton, N.J.) · 2024
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  11. Widespread amyloid aggregates formation by Zika virus proteins and peptides.Protein science : a publication of the Protein Society · 2023
    Article
  12. A suitable model to investigate acute neurological consequences of coronavirus infection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Isabella G OlmoDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Toniana G CarvalhoDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Vivian V CostaDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Juliana Alves-SilvaDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Carolina Z FerrariDepartment of Pharmacology, ICB, UFMG, Belo Horizonte, Brazil.
Tatiane C Izidoro-ToledoDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Juliana F da SilvaInstitute of Education and Research Santa Casa, Belo Horizonte, Brazil.
Antonio L TeixeiraNeuropsychiatry Program, Department of Psychiatry and Behavioral Science, UT Health, Houston, TX, United States.
Danielle G SouzaDepartment of Microbiology, ICB, UFMG, Belo Horizonte, Brazil.
Joao T MarquesDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Mauro M TeixeiraDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Luciene B VieiraDepartment of Pharmacology, ICB, UFMG, Belo Horizonte, Brazil.
Fabiola M RibeiroDepartment of Biochemistry and Immunology, Institute of Biological Sciences (ICB), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Universidade Federal de Minas Gerais · BRInsper · BRThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zika virus (ZIKV) has recently caused a worldwide outbreak of infections associated with severe neurological complications, including microcephaly in infants born from infected mothers. ZIKV exhibits high neurotropism and promotes neuroinflammation and neuronal cell death. We have recently demonstrated that

Indexed as

GluN2Binterleukin-1βN-methyl-d-aspartate receptorstumor necrosis factor-αZika virus

Identifiers

PMID28878777
PMCPMC5572413
OpenAlexW2747026281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.