Evidence map›Paper›PMID 28878689›Full record

ArticleFrontiers in physiology2017

A20/TNFAIP3 Discriminates Tumor Necrosis Factor (TNF)-Induced NF-κB from JNK Pathway Activation in Hepatocytes.

Federico Pinna, Michaela Bissinger, Katharina Beuke, Nicolas Huber, Thomas Longerich, Ursula Kummer, Peter Schirmacher, Sven Sahle, Kai Breuhahn

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  4. A Model of iPSC-Derived Macrophages withInternational journal of molecular sciences · 2023
    Article
  5. YTHDF2/mThe EMBO journal · 2023
    Article
  6. Regulation of apoptosis by ubiquitination in liver cancer.American journal of cancer research · 2023
    Review
  7. Article
  8. Article
  9. ABIN1 alleviates inflammatory responses and colitisTherapeutic advances in chronic disease · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Federico PinnaMolecular Hepatopathology, Institute of Pathology, University Hospital HeidelbergHeidelberg, Germany.
Michaela BissingerMolecular Hepatopathology, Institute of Pathology, University Hospital HeidelbergHeidelberg, Germany.
Katharina BeukeDepartment of Modeling of Biological Processes, Centre for Organismal Studies, BioQuant, University of HeidelbergHeidelberg, Germany.
Nicolas HuberDepartment of Modeling of Biological Processes, Centre for Organismal Studies, BioQuant, University of HeidelbergHeidelberg, Germany.
Thomas LongerichInstitute of Pathology, RWTH Aachen University HospitalAachen, Germany.
Ursula KummerDepartment of Modeling of Biological Processes, Centre for Organismal Studies, BioQuant, University of HeidelbergHeidelberg, Germany.
Peter SchirmacherMolecular Hepatopathology, Institute of Pathology, University Hospital HeidelbergHeidelberg, Germany.
Sven SahleDepartment of Modeling of Biological Processes, Centre for Organismal Studies, BioQuant, University of HeidelbergHeidelberg, Germany.
Kai BreuhahnMolecular Hepatopathology, Institute of Pathology, University Hospital HeidelbergHeidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the liver tumor necrosis factor (TNF)-induced signaling critically regulates the immune response of non-parenchymal cells as well as proliferation and apoptosis of hepatocytes

Indexed as

apoptosiscomputational modelingdecision-making processhepatocellular carcinomahepatocyte

Identifiers

PMID28878689
PMCPMC5572400
OpenAlexW2749024757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.