ArticleScientific reports2017
Environmental stress is the major cause of transcriptomic and proteomic changes in GM and non-GM plants.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The ladder-shape melting temperature isothermal amplification methods for detection of CaMV 35S and CP4 EPSPS genes in soybean foods.Transgenic research · 2026Article
- Genetically modified crops and sustainable development: navigating challenges and opportunities.Food science and biotechnology · 2025Review
- Long noncoding RNA transcriptome analysis reveals novel lncRNAs in Morus alba 'Yu-711' response to drought stress.The plant genome · 2024Article
- Field test of Easter lilies transformed with a rice cystatin gene for root lesion nematode resistance.Frontiers in plant science · 2023Article
- Transcriptomic Analysis of Mature Transgenic Poplar Expressing the Transcription FactorFrontiers in bioengineering and biotechnology · 2022Article
- Genetically engineered crops for sustainably enhanced food production systems.Frontiers in plant science · 2022Review
- Metabolic Analysis RevealsMetabolites · 2021Article
- Evaluation of the use of untargeted metabolomics in the safety assessment of genetically modified crops.Metabolomics : Official journal of the Metabolomic Society · 2020Review
- Plant breeding involving genetic engineering does not result in unacceptable unintended effects in rice relative to conventional cross-breeding.The Plant journal : for cell and molecular biology · 2020Article
- The barley stripe mosaic virus expression system reveals the wheat C2H2 zinc finger protein TaZFP1B as a key regulator of drought tolerance.BMC plant biology · 2020Article
- Climatic changes and potatoes: How can we cope with the abiotic stresses?Breeding science · 2019Review
- The evolving EU regulatory framework for precision breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
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6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The approval of genetically modified (GM) crops is preceded by years of intensive research to demonstrate safety to humans and environment. We recently showed that in vitro culture stress is the major factor influencing proteomic differences of GM vs. non-GM plants. This made us question the number of generations needed to erase such "memory". We also wondered about the relevance of alterations promoted by transgenesis as compared to environment-induced ones. Here we followed three rice lines (1-control, 1-transgenic and 1-negative segregant) throughout eight generations after transgenesis combining proteomics and transcriptomics, and further analyzed their response to salinity stress on the F6 generation. Our results show that: (a) differences promoted during genetic modification are mainly short-term physiological changes, attenuating throughout generations, and (b) environmental stress may cause far more proteomic/transcriptomic alterations than transgenesis. Based on our data, we question what is really relevant in risk assessment design for GM food crops.
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