Evidence map›Paper›PMID 28878181›Full record

Trial reportNutrients2017

Developmental Outcomes at 24 Months of Age in Toddlers Supplemented with Arachidonic Acid and Docosahexaenoic Acid: Results of a Double Blind Randomized, Controlled Trial.

Angela M Devlin, Cecil M Y Chau, Roger Dyer, Julie Matheson, Deanna McCarthy, Karin Yurko-Mauro, Sheila M Innis, Ruth E Grunau

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01263912 (Essential Fatty Acid Nutrition in Infants 1 to 2 Years-of-Age), which is not on this map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01263912 nacompletednot on this map

Essential Fatty Acid Nutrition in Infants 1 to 2 Years-of-Age

TypeinterventionalSponsorUniversity of British ColumbiaRan2010 to 2016Enrolled133ConditionsInfant NutritionArmsLCPUFA Supplement, Placebo
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Angela M DevlinDepartment of Pediatrics, University of British Columbia, BC Children's Hospital Research Institute, A4-194 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada. adevlin@bcchr.ubc.ca.
Cecil M Y ChauDepartment of Pediatrics, University of British Columbia, BC Children's Hospital Research Institute, A4-194 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada. cchau@bcchr.ca.
Roger DyerDepartment of Pediatrics, University of British Columbia, BC Children's Hospital Research Institute, A4-194 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada. radyer@mail.ubc.ca.ORCID 0000-0003-2009-1563
Julie MathesonDepartment of Pediatrics, University of British Columbia, BC Children's Hospital Research Institute, A4-194 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada. jmatheson@bcchr.ca.
Deanna McCarthyDSM Nutritional Products, Columbia, MD 21045, USA. Deanna.McCarthy@dsm.com.
Karin Yurko-MauroDSM Nutritional Products, Columbia, MD 21045, USA. Karin.Yurko-Mauro@dsm.com.
Sheila M InnisDepartment of Pediatrics, University of British Columbia, BC Children's Hospital Research Institute, A4-194 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada. rgrunau@bcchr.ca.
Ruth E GrunauDepartment of Pediatrics, University of British Columbia, BC Children's Hospital Research Institute, A4-194 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada.
University of British Columbia · CANutrition 21 (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about arachidonic acid (ARA) and docosahexaenoic acid (DHA) requirements in toddlers. A longitudinal, double blind, controlled trial in toddlers (

Indexed as

Child DevelopmentAge FactorsArachidonic AcidBritish ColumbiaChild LanguageChild, PreschoolCognitionDietary SupplementsDocosahexaenoic AcidsDouble-Blind MethodErythrocytesFemaleHumansInfantIntelligenceMaleArachidonic AcidDocosahexaenoic AcidsPhosphatidylcholinesphosphatidylethanolaminePhosphatidylethanolaminesarachidonic aciddocosahexaenoic acidlong chain polyunsaturated fatty acidsneurodevelopmenttoddlers

Identifiers

PMID28878181
PMCPMC5622735
OpenAlexW2752032852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.