Evidence map›Paper›PMID 28878088›Full record

ArticleJournal of virology2017

Effect of Polymorphisms at Codon 146 of the Goat PRNP Gene on Susceptibility to Challenge with Classical Scrapie by Different Routes.

Penelope Papasavva-Stylianou, Marion Mathieson Simmons, Angel Ortiz-Pelaez, Otto Windl, John Spiropoulos, Soteria Georgiadou

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. First Report of Polymorphisms and Genetic Characteristics ofAnimals : an open access journal from MDPI · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Goats naturally devoid of PrPVeterinary research · 2020
    Article
  11. Transmissible spongiform encephalopathy in goats: is PrP rapid test sensitivity affected by genotype?Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Penelope Papasavva-StylianouVeterinary Services, Nicosia, Cyprus.
Marion Mathieson SimmonsAnimal and Plant Health Agency, New Haw, Addlestone, Surrey, United Kingdom.
Angel Ortiz-PelaezAnimal and Plant Health Agency, New Haw, Addlestone, Surrey, United Kingdom.
Otto WindlAnimal and Plant Health Agency, New Haw, Addlestone, Surrey, United Kingdom.
John SpiropoulosAnimal and Plant Health Agency, New Haw, Addlestone, Surrey, United Kingdom john.spiropoulos@apha.gsi.gov.uk.
Soteria GeorgiadouVeterinary Services, Nicosia, Cyprus.
Animal and Plant Health Agency · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report presents the results of experimental challenges of goats with scrapie by both the intracerebral (i.c.) and oral routes, exploring the effects of polymorphisms at codon 146 of the goat

Indexed as

Amino Acid SubstitutionCodonGenetic Predisposition to DiseasePolymorphism, GeneticAnimalsGoatsPrion ProteinsScrapieCodonPrion Proteinscodon 146goatsPRNPPrPresistancescrapiesusceptibility

Identifiers

PMID28878088
PMCPMC5660499
OpenAlexW2750710517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.