Evidence map›Paper›PMID 28878080›Full record

ArticleJournal of virology2017

Mechanical Barriers Restrict Invasion of Herpes Simplex Virus 1 into Human Oral Mucosa.

Katharina Thier, Philipp Petermann, Elena Rahn, Daniel Rothamel, Wilhelm Bloch, Dagmar Knebel-Mörsdorf

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Herpes Simplex Virus Type 1 Infection of Human Periodontal Ligament.International journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. HPV related p16BMC oral health · 2024
    Article
  12. Journal of virology · 2023
    Article
  13. Article
  14. Bio-protocol · 2022
    Article
  15. Journal of virology · 2021
    Article
  16. Article
  17. Herpes Simplex Virus Type 1 Interactions with the Interferon System.International journal of molecular sciences · 2020
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Katharina ThierCenter for Biochemistry, University of Cologne, Cologne, Germany.
Philipp PetermannCenter for Biochemistry, University of Cologne, Cologne, Germany.
Elena RahnCenter for Biochemistry, University of Cologne, Cologne, Germany.
Daniel RothamelDepartment of Oral and Maxillofacial Plastic Surgery, University of Cologne, Cologne, Germany.
Wilhelm BlochDepartment of Molecular and Cellular Sports Medicine, German Sports University, Cologne, Germany.
Dagmar Knebel-MörsdorfCenter for Biochemistry, University of Cologne, Cologne, Germany dagmar.moersdorf@uni-koeln.de.
University of Cologne · DEGerman Sport University Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral mucosa is one of the main target tissues of the human pathogen herpes simplex virus 1 (HSV-1). How the virus overcomes the protective epithelial barriers and penetrates the tissue to reach its receptors and initiate infection is still unclear. Here, we established an

Indexed as

Immunity, InnateFemaleHerpes SimplexHerpesvirus 1, HumanHumansKeratinocytesMaleMouth Mucosaepithelial barrierHSV-1HVEMkeratinocytesLangerhans cellsmechanical woundingnectin-1oral human mucosaviral invasion

Identifiers

PMID28878080
PMCPMC5660485
OpenAlexW2750886231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.