ArticleProceedings of the National Academy of Sciences of the United States of America2017
CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma.Nature cell biology · 2025Article
- PARInternational journal of molecular sciences · 2025Article
- Deep Learning With Optical Coherence Tomography for Melanoma Identification and Risk Prediction.Journal of biophotonics · 2025Article
- ROS and calcium signaling are critical determinant of skin pigmentation.Cell calcium · 2025Review
- Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression.iScience · 2023Article
- Building and Maintaining the Skin.Cold Spring Harbor perspectives in biology · 2022Review
- Implications of Oxidative Stress in the Pathogenesis and Treatment of Hyperpigmentation Disorders.Oxidative medicine and cellular longevity · 2022Review
- UV-induced reduction in Polycomb repression promotes epidermal pigmentation.Developmental cell · 2021Article
- In Vivo Longitudinal Tracking of Lymphangiogenesis and Angiogenesis in Cutaneous Melanoma Mouse Model Using Multifunctional Optical Coherence Tomography.JID innovations : skin science from molecules to population health · 2021Article
- Skin pigmentation and its control: From ultraviolet radiation to stem cells.Experimental dermatology · 2021Review
- Identification of a Potentially Functional circRNA-miRNA-mRNA Regulatory Network in Melanocytes for Investigating Pathogenesis of Vitiligo.Frontiers in genetics · 2021Article
- Functions and regulation of the serine/threonine protein kinase CK1 family: moving beyond promiscuity.The Biochemical journal · 2020Review
- Casein kinase 1α inhibits p53 downstream of MDM2‑mediated autophagy and apoptosis in acute myeloid leukemia.Oncology reports · 2020Article
- Lymphatic vessel segmentation in optical coherence tomography by adding U-Net-based CNN for artifact minimization.Biomedical optics express · 2020Article
- Casein kinase 1α decreases β-catenin levels at adherens junctions to facilitate wound closure inDevelopment (Cambridge, England) · 2019Article
- FAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.EMBO reports · 2019Article
- Super-enhancers: critical roles and therapeutic targets in hematologic malignancies.Journal of hematology & oncology · 2019Review
- The role of p53 in developmental syndromes.Journal of molecular cell biology · 2019Review
- PathogenicWellcome open research · 2019Article
- Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin.Cancer research · 2018Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Casein kinase 1α (CK1α), a component of the β-catenin destruction complex, is a critical regulator of Wnt signaling; its ablation induces both Wnt and p53 activation. To characterize the role of CK1α (encoded by
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.