Evidence map›Paper›PMID 28877993›Full record

ArticleThe Journal of cell biology2017

Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ

Xiaoyi Qu, Feng Ning Yuan, Carlo Corona, Silvia Pasini, Maria Elena Pero, Gregg G Gundersen, Michael L Shelanski, Francesca Bartolini

Abstract read
In one paragraph

Article in The Journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Review
  2. Amyloid Beta Oligomers as Early Triggers of Neuronal Cytoskeleton Dysfunction in Alzheimer's Disease.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry.International journal of molecular sciences · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Synaptogenic effect ofScience translational medicine · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoyi QuDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY.
Feng Ning YuanDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY.ORCID 0000-0003-3208-7262
Carlo CoronaDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY.
Silvia PasiniDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY.
Maria Elena PeroDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY.
Gregg G GundersenDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY.
Michael L ShelanskiDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY.
Francesca BartoliniDepartment of Pathology, Anatomy and Cell Biology, Columbia University, New York, NY fb2131@cumc.columbia.edu.ORCID 0000-0003-1048-622X

Funding

Pathogenic Roles for Microtubule Stabilization Pathways in Alzheimers diseaseR01AG050658 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Francesca Bartolini · 2016 to 2026
$3.5M
Pathogenic Roles for Microtubule Stabilization Pathways in Alzheimers diseaseRF1AG050658 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARTOLINI, FRANCESCA · 2022 to 2022
$2.4M
Pathogenic Roles for Microtubule Stabilization Pathways in Alzheimer's DiseaseR56AG050658 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARTOLINI, FRANCESCA · 2021 to 2021
$755k
NIA NIH HHS R01 AG050658NIA NIH HHS R56 AG050658NIA NIH HHS RF1 AG050658
6 · The paper itself

Abstract

Oligomeric Amyloid β

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAxonsCarrier ProteinsCytochrome-B(5) ReductaseDendritic SpinesForminsMiceMice, KnockoutMicrotubulesPeptide FragmentsProtein Processing, Post-TranslationalProtein TransportRatsRats, Sprague-DawleyAmyloid beta-Peptidesamyloid beta-protein (1-42)Carrier ProteinsCyb5R3 protein, ratCytochrome-B(5) ReductaseDiap1 protein, mouseForminsPeptide Fragmentstau Proteins

Identifiers

PMID28877993
PMCPMC5626542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.