Evidence map›Paper›PMID 28877985›Full record

ArticleMolecular biology of the cell2017

MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication.

Akiko Kumagai, William G Dunphy

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Akiko KumagaiDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
William G DunphyDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125 dunphy@caltech.edu.

Funding

Role of ATR in Cell Cycle CheckpointsR01GM070891 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI DUNPHY, WILLIAM G · 2004 to 2018
$5.7M
ENZYMOLOGY OF MITOSIS PROMOTING FACTOR (MPF)R01GM043974 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI DUNPHY, WILLIAM G · 1990 to 2022
$4.0M
Enzymology of Mitosis Promoting Factor (MPF)R37GM043974 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI DUNPHY, WILLIAM G · 2002 to 2011
$4.0M
NIGMS NIH HHS R01 GM043974NIGMS NIH HHS R01 GM070891NIGMS NIH HHS R37 GM043974
6 · The paper itself

Abstract

Treslin, which is essential for incorporation of Cdc45 into the replicative helicase, possesses a partner called MTBP (Mdm2-binding protein). We have analyzed

Indexed as

AnimalsCarrier ProteinsCell Cycle ProteinsChromatinDNA-Binding ProteinsDNA HelicasesDNA ReplicationHumansNuclear ProteinsPhosphorylationProtein DomainsS PhaseXenopusXenopus laevisXenopus ProteinsCarrier ProteinsCell Cycle ProteinsChromatinDNA-Binding ProteinsDNA HelicasesMTBP protein, humanNuclear ProteinsTICRR protein, humanXenopus Proteins

Identifiers

PMID28877985
PMCPMC5662258

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.