Evidence map›Paper›PMID 28877958›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression.

Henning Hagmann, Nicole Mangold, Markus M Rinschen, Tim Koenig, Karl Kunzelmann, Bernhard Schermer, Thomas Benzing, Paul T Brinkkoetter

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. The odyssey of the TR(i)P journey to the cellular membrane.Frontiers in cell and developmental biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Henning HagmannDepartment II of Internal Medicine, Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Nicole MangoldDepartment II of Internal Medicine, Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Markus M RinschenDepartment II of Internal Medicine, Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Tim KoenigCologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Karl KunzelmannDepartment of Physiology, University Regensburg, Regensburg, Germany.
Bernhard SchermerDepartment II of Internal Medicine, Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Thomas BenzingDepartment II of Internal Medicine, Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Paul T BrinkkoetterDepartment II of Internal Medicine, Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany; paul.brinkkoetter@uk-koeln.de.
University of Cologne · DECologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · DEMax Planck Institute for Biology of Ageing · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Signaling

Indexed as

Amino Acid SequenceAnimalsBinding SitesConserved SequenceCyclin-Dependent Kinase 5Extracellular Signal-Regulated MAP KinasesFemaleHEK293 CellsHeLa CellsHumansIn Vitro TechniquesOocytesPhosphorylationProline-Directed Protein KinasesProtein StabilityProteomicsCDK5 protein, humanCyclin-Dependent Kinase 5Extracellular Signal-Regulated MAP KinasesProline-Directed Protein KinasesRecombinant ProteinsTRPC6 Cation ChannelTRPC6 protein, humancyclin-dependent kinase 5glomerular diseaseMAPKpodocyteproteinuria

Identifiers

PMID28877958
PMCPMC5731127
OpenAlexW2753401870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.