Evidence map›Paper›PMID 28877929›Full record

ArticleClinical and vaccine immunology : CVI2017

Merozoite Surface Protein 1 from Plasmodium falciparum Is a Major Target of Opsonizing Antibodies in Individuals with Acquired Immunity against Malaria.

Anja Jäschke, Boubacar Coulibaly, Edmond J Remarque, Hermann Bujard, Christian Epp

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Targeting theHeliyon · 2022
    Review
  9. Article
  10. Article
  11. Review
  12. Naturally Acquired Humoral Immunity AgainstFrontiers in immunology · 2020
    Review
  13. Immunization with full-lengthNPJ vaccines · 2020
    Article
  14. [Development of malaria vaccines-state of the art].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Novel Strategies for Malaria Vaccine Design.Frontiers in immunology · 2018
    Review
  19. Review
  20. Neutrophils and Malaria.Frontiers in immunology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Anja JäschkeCenter for Infectious Diseases, Parasitology, University Hospital Heidelberg, Heidelberg, Germany.
Boubacar CoulibalyCentre de Recherche en Santé de Nouna, Nouna, Burkina Faso.
Edmond J RemarqueBiomedical Primate Research Center, Department of Virology, Rijswijk, The Netherlands.
Hermann BujardCenter for Molecular Biology, University of Heidelberg, Heidelberg, Germany h.bujard@zmbh.uni-heidelberg.de.
Christian EppCenter for Infectious Diseases, Parasitology, University Hospital Heidelberg, Heidelberg, Germany.
University Hospital Heidelberg · DEBiomedical Primate Research Centre · NLCentre de Recherche en Santé de Nouna · BFHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naturally acquired immunity against malaria is largely mediated by serum antibodies controlling levels of blood-stage parasites. A limited understanding of the antigenic targets and functional mechanisms of protective antibodies has hampered the development of efficient malaria vaccines. Besides directly inhibiting the growth of

Indexed as

Adaptive ImmunityAnimalsAntibodies, ProtozoanAntigens, ProtozoanBurkina FasoHumansImmunoglobulin GMacaca mulattaMalaria, FalciparumMalaria VaccinesMerozoitesMerozoite Surface Protein 1Neutrophil ActivationNeutrophilsOpsonin ProteinsPlasmodium falciparumAntibodies, ProtozoanAntigens, ProtozoanImmunoglobulin GMalaria VaccinesMerozoite Surface Protein 1Opsonin ProteinsADRBneutrophilopsonizing antibodiesP. falciparum MSP-1respiratory burst

Identifiers

PMID28877929
PMCPMC5674199
OpenAlexW2752593382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.