ArticlePloS one2017
Transcriptomic profiling in muscle and adipose tissue identifies genes related to growth and lipid deposition.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 33 citations in OpenAlex.
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- Genome-Wide Association Study for Individual Primal Cut Quality Traits in Canadian Commercial Crossbred Pigs.Animals : an open access journal from MDPI · 2025Article
- Effects of Acorns on Fatty Acid Composition and Lipid Metabolism in Adipose Tissue of Yuxi Black Pigs.Animals : an open access journal from MDPI · 2024Article
- Transcriptomic profiling of backfat and muscle in Lijiang pigs with divergent body size across growth stages.Scientific reports · 2024Article
- Comparative transcriptome analysis of longissimus dorsi muscle reveal potential genes affecting meat trait in Chinese indigenous Xiang pig.Scientific reports · 2024Article
- LncGenes · 2023Article
- Identification of transcriptional regulatory variants in pig duodenum, liver, and muscle tissues.GigaScience · 2022Article
- Age Evolution of Lipid Accretion Rate in Boars Selected for Lean Meat and Duroc Barrows.Animals : an open access journal from MDPI · 2022Article
- Transcriptomics-Based Study of Differentially Expressed Genes Related to Fat Deposition in Tibetan and Yorkshire Pigs.Frontiers in veterinary science · 2022Article
- Gene Expression and Carcass Traits Are Different between Different Quality Grade Groups in Red-Faced Hereford Steers.Animals : an open access journal from MDPI · 2021Article
- Single-Step Genome Wide Association Study Identifies QTL Signals for Untrimmed and Trimmed Thigh Weight in Italian Crossbred Pigs for Dry-Cured Ham Production.Animals : an open access journal from MDPI · 2021Article
- Identification of Differentially Expressed Genes and Lipid Metabolism Signaling Pathways between Muscle and Fat Tissues in Broiler Chickens.The journal of poultry science · 2021Article
- Genome-Wide Detection of Runs of Homozygosity in Laiwu Pigs Revealed by Sequencing Data.Frontiers in genetics · 2021Article
- Lipid Deposition and Metabolism in Local and Modern Pig Breeds: A Review.Animals : an open access journal from MDPI · 2020Review
- Data Mining and Validation of AMPK Pathway as a Novel Candidate Role Affecting Intramuscular Fat Content in Pigs.Animals : an open access journal from MDPI · 2019Article
- Gene co-expression networks associated with carcass traits reveal new pathways for muscle and fat deposition in Nelore cattle.BMC genomics · 2019Article
- Identification of lncRNAs and Genes Responsible for Fatness and Fatty Acid Composition Traits between the Tibetan and Yorkshire Pigs.International journal of genomics · 2019Article
- Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Growth performance and meat quality are important traits for the pig industry and consumers. Adipose tissue is the main site at which fat storage and fatty acid synthesis occur. Therefore, we combined high-throughput transcriptomic sequencing in adipose and muscle tissues with the quantification of corresponding phenotypic features using seven Chinese indigenous pig breeds and one Western commercial breed (Yorkshire). We obtained data on 101 phenotypic traits, from which principal component analysis distinguished two groups: one associated with the Chinese breeds and one with Yorkshire. The numbers of differentially expressed genes between all Chinese breeds and Yorkshire were shown to be 673 and 1056 in adipose and muscle tissues, respectively. Functional enrichment analysis revealed that these genes are associated with biological functions and canonical pathways related to oxidoreductase activity, immune response, and metabolic process. Weighted gene coexpression network analysis found more coexpression modules significantly correlated with the measured phenotypic traits in adipose than in muscle, indicating that adipose regulates meat and carcass quality. Using the combination of differential expression, QTL information, gene significance, and module hub genes, we identified a large number of candidate genes potentially related to economically important traits in pig, which should help us improve meat production and quality.
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