SynthesisArquivos brasileiros de cardiologia2017
Functional Capacity in Congenital Heart Disease: A Systematic Review and Meta-Analysis.
Synthesis in Arquivos brasileiros de cardiologia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06448520 (Reference Values for the Muscle Power Sprint Test in Children Aged 5-12 Years), which is not on this map. Cited by 15 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Reference Values for the Muscle Power Sprint Test in Children Aged 5-12 Years
Who cites it
15 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Risk of Cancer in Patients with Congenital Heart Disease: A Systematic Review and Meta-Analysis.Cardiology · 2025Pooled it
- Examining the Role of Exercise Training in Enhancing Life for Adult Congenital Heart Disease: Systematic Review.Arquivos brasileiros de cardiologia · 2024Pooled it
- Brazilian Guideline for Exercise Testing in Children and Adolescents - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Effects of Aerobic Exercise on Cardiopulmonary Function in Postoperative Patients with Congenital Heart Disease: A Meta-analysis.Reviews in cardiovascular medicine · 2024Pooled it
- Submaximal Field Walking Tests Applied in the Cardiopulmonary Assessment in Congenital Heart Diseases: A Systematic Review.Current pediatric reviews · 2024Pooled it
- Exercise Capacity in Children and Adolescents With Congenital Heart Disease: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Daily physical activity and cardiorespiratory fitness in adults with Down syndrome with and without congenital heart disease.Disability and health journal · 2025Trial
- Investigation of Community Integration in Adults with Congenital Heart Disease Within the Scope of International Classification of Functioning, Disability, and Health.Pediatric cardiology · 2026Article
- Article
- Activities of Daily Living, Physical Activity, Physical Fitness and Quality of Life in Children with Congenital Heart Disease: A Case-Control Study.Arquivos brasileiros de cardiologia · 2023Article
- Impact of Preoperative Functional Capacity on Postoperative Outcomes in Congenital Heart Surgery: An Observational and Prospective Study.Arquivos brasileiros de cardiologia · 2022Observational
- Novel Point Mutations in 3'-Untranslated Region of GATA4 Gene Are Associated with Sporadic Non-syndromic Atrial and Ventricular Septal Defects.Current medical science · 2022Article
- Reduced Forced Vital Capacity and the Number of Chest Wall Surgeries are Associated with Decreased Exercise Capacity in Children with Congenital Heart Disease.Pediatric cardiology · 2022Article
- Three-dimensional alignment of microvasculature and cardiomyocytes in the developing ventricle.Scientific reports · 2020Article
- Caregiving Strategies in Families of Children with Congenital Heart Disease: A Qualitative Study.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildren and adolescents with congenital heart disease often have alterations in their exercise capacity that can be evaluated by various functional testing.
objectiveTo evaluate the functional capacity of children and adolescents with congenital heart disease (CHD) with systematic review and meta-analyses.
methodsThe review included observational studies, data from the first evaluation of randomized clinical trials or observational follow-up periods after clinical trials which evaluated functional capacity by cardiopulmonary exercise test, stress testing, six-minute walk test or step test, in children and adolescents with CHD, aged between six and 18 years, and comparisons with healthy controls in the same age group. The quantitative assessment was performed by meta-analysis, by comparing the maximal oxygen consumption (VO2max) of children and adolescents with CHD and respective control groups.
resultsTwenty-five of 2.683 studies identified in the search met the inclusion criteria. The VO2max measurement showed that patients with CHD have a decrease of 9.31 ml/Kg/min (95% CI. -12.48 to -6.13; I2, 94.3%, P for heterogeneity < 0.001) compared with the control group. The meta-analysis of the data of maximum heart rate (HR) reached during cardiopulmonary test and stress testing, retrieved from 18 studies, showed a HR value of -15.14 bpm (95% CI. -20.97 to -9.31; I2, 94.3%, P for heterogeneity < 0.001) compared with the control group.
conclusionChildren and adolescents with CHD have lower VO2max and HR compared to controls.
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