Evidence map›Paper›PMID 28876228›Full record

ArticleActa crystallographica. Section F, Structural biology communications2017

HicAB toxin-antitoxin complex from Escherichia coli: expression and crystallization.

Jingsi Yang, Bingshuang Xu, Zengqiang Gao, Ke Zhou, Peng Liu, Yuhui Dong, Jianjun Zhang, Quansheng Liu

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Viruses · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jingsi YangCollege of Chemistry, Dalian University of Technology, 2 Linggong Road, Ganjingzi District, Dalian 116024, People's Republic of China.
Bingshuang XuMulti-Discipline Research Center, Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Beijing 100049, People's Republic of China.
Zengqiang GaoMulti-Discipline Research Center, Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Beijing 100049, People's Republic of China.
Ke ZhouMulti-Discipline Research Center, Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Beijing 100049, People's Republic of China.
Peng LiuMulti-Discipline Research Center, Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Beijing 100049, People's Republic of China.
Yuhui DongMulti-Discipline Research Center, Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Beijing 100049, People's Republic of China.
Jianjun ZhangCollege of Chemistry, Dalian University of Technology, 2 Linggong Road, Ganjingzi District, Dalian 116024, People's Republic of China.
Quansheng LiuMulti-Discipline Research Center, Institute of High Energy Physics, Chinese Academy of Sciences, Yuquan Road 19B, Beijing 100049, People's Republic of China.
Institute of High Energy Physics · CNDalian University of Technology · CN

Funding

National Basic Research Program of China 2012CB917201National Natural Science Foundation of China 11179022National Natural Science Foundation of China 31170689National Natural Science Foundation of China 31570761Strategic Priority Research Program of the Chinese Academy of Sciences XDB08030103
6 · The paper itself

Abstract

Toxin-antitoxin (TA) systems are widespread in both bacteria and archaea, where they enable cells to adapt to environmental cues. TA systems play crucial roles in various cellular processes, such as programmed cell death, cell growth, persistence and virulence. Here, two distinct forms of the type II toxin-antitoxin complex HicAB were identified and characterized in Escherichia coli K-12, and both were successfully overexpressed and purified. The two proposed forms, HicAB

Indexed as

AntitoxinsBacterial ToxinsCrystallizationCrystallography, X-RayEscherichia coliEscherichia coli ProteinsAntitoxinsBacterial ToxinsEscherichia coli Proteinscell stressEscherichia coliHicABpersister cellstoxin–antitoxin systems

Identifiers

PMID28876228
PMCPMC5619741
OpenAlexW2747071551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.